Chronic Migraine: Current Treatment Options and Recent Advances

An overview of the role of neuroimaging in understanding the structure and function of the brain in patients with migraine.

A review of the classification of migraine versus cluster headaches, including a comparison of episodic versus chronic disease.

Peter Goadsby, MBBS, provides a historical perspective on the evolution of clinical management, and therapies for preventive and acute chronic migraine.

Experts review the introduction of novel therapies available for chronic migraine prevention.

A discussion on the criteria used to determine the choice of therapy for patients with migraine, with insight on evidence-based acute treatments, as well as preventive options.

Migraine specialists discuss the management of treatment-related adverse effects associated with the use of triptans for patients with migraine.

Richard B. Lipton, MD, and Stephen Silberstein, MD, comment on the recommended protocol for patients seen in the emergency department and discuss when inpatient care is necessary for the treatment of chronic migraine.

Experts expand on available preventive treatment options for chronic migraine, including FDA-approved calcitonin gene-related peptide (CGRP) inhibitors and neuromodulatory devices.

Migraine specialists discuss the excitement surrounding CGRP (calcitonin gene-related peptide) targeted therapy and discuss the efficacy and safety advantages over existing treatment options.

A review of the results from the phase 3 STRIVE and ARISE trials looking at erenumab (Aimovig) as a preventive therapy for migraine, including anecdotes of personal experiences from 2 migraine experts.

An in-depth update and comparison of the calcitonin gene-related peptide (CGRP) targeted agents in development for the treatment of chronic migraine.

A review of complementary/alternative therapies, including a discussion on the importance of lifestyle modifications for patients suffering from chronic migraine.

Migraine experts provide personal perspectives on the best approaches for treating refractory chronic migraines.

Richard B. Lipton, MD; Stephen Silberstein, MD; and Peter Goadsby, MBBS, provide closing thoughts on the progress that has been made in migraine research and provide positive outlooks on the future of chronic migraine treatment.
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