NeurologyLive - Clinical Neurology News and Neurology Expert Insights articleshttps://www.neurologylive.com/newsNeurologyLive - Clinical Neurology News and Neurology Expert Insights articles© 2026 MJH Life Sciences™ and NeurologyLive - Clinical Neurology News and Neurology Expert Insights. All rights reserved.Sat, 15 Aug 2026 02:51:17 +00005en-us14447https://www.neurologylive.com/newshttps://www.neurologylive.com/logo.webphttps://www.neurologylive.com/view/cn045-promotes-oligodendrocyte-maturation-modest-remyelination-preclinical-ms-studyhttps://www.neurologylive.com/view/cn045-promotes-oligodendrocyte-maturation-modest-remyelination-preclinical-ms-study<![CDATA[Experimental small molecule CN045 promoted oligodendrocyte maturation and modest remyelination in preclinical models of multiple sclerosis, supporting further development of the compound as a potential remyelination therapy.]]>Fri, 14 Aug 2026 22:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/neurologylive-friday-5-august-14-2026https://www.neurologylive.com/view/neurologylive-friday-5-august-14-2026<![CDATA[Take 5 minutes to catch up on NeurologyLive®'s highlights from the week ending August 14, 2026. ]]>Fri, 14 Aug 2026 19:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/the-future-of-blood-based-biomarkers-alzheimer-diseasehttps://www.neurologylive.com/view/the-future-of-blood-based-biomarkers-alzheimer-disease<![CDATA[In the final episode, Yogesh Shah, MD, MPH, FAAFP, details how Alzheimer biomarkers have evolved and why blood-based testing could move the field toward earlier detection, risk reduction, and ultimately prevention.]]>Fri, 14 Aug 2026 17:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/pacap-in-migraine-bridging-preclinical-studies-clinical-translationhttps://www.neurologylive.com/view/pacap-in-migraine-bridging-preclinical-studies-clinical-translation<![CDATA[Clinician author Kevin Chang, PharmD, writes about PACAP as a distinct, druggable migraine pathway independent of CGRP, offering a promising option for patients who don't respond to current therapies.]]>Fri, 14 Aug 2026 15:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/fda-approves-tau-pet-tracer-mk-6240-alzheimer-diagnostic-workuphttps://www.neurologylive.com/view/fda-approves-tau-pet-tracer-mk-6240-alzheimer-diagnostic-workup<![CDATA[The FDA approved TAUKLARIFY (florquinitau F 18 injection), a tau PET imaging agent, for identifying tau neurofibrillary tangle pathology in adults being evaluated for Alzheimer disease.]]>Fri, 14 Aug 2026 12:49:56 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/brain-chat-stronger-together-communicating-care-partners-chronic-diseasehttps://www.neurologylive.com/view/brain-chat-stronger-together-communicating-care-partners-chronic-disease<![CDATA[Mitzi Joi Williams, MD, is joined by Charnetta Colton Poole, MD, to discuss the challenges of communication between people living with chronic illness and their care partners, including maintaining autonomy, navigating changing roles, and building collaborative relationships through open communication.]]>Fri, 14 Aug 2026 10:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/voyager-advance-2-tau-targeted-alzheimer-therapies-toward-key-clinical-milestoneshttps://www.neurologylive.com/view/voyager-advance-2-tau-targeted-alzheimer-therapies-toward-key-clinical-milestones<![CDATA[Voyager Therapeutics is advancing 2 tau-targeted Alzheimer disease therapies toward key clinical milestones expected in the fourth quarter of 2026, including tau PET imaging data for VY7523 and first-in-human dosing for VY1706.]]>Thu, 13 Aug 2026 22:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/fda-clears-phase-2-trial-demyelinating-agent-lucid-ms-progressive-multiple-sclerosishttps://www.neurologylive.com/view/fda-clears-phase-2-trial-demyelinating-agent-lucid-ms-progressive-multiple-sclerosis<![CDATA[The FDA has cleared Quantum BioPharma's investigational new drug application for Lucid-MS, allowing the company to begin a phase 2 trial of the first-in-class demyelination-targeting compound in progressive multiple sclerosis.]]>Thu, 13 Aug 2026 19:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/fellowship-practice-career-advice-early-career-neurologistshttps://www.neurologylive.com/view/fellowship-practice-career-advice-early-career-neurologists<![CDATA[Uma Menon, MD, Adult Neurology Residency Program Director at Allina Health, shares lessons on navigating fellowship, finding the right career path, building expertise, and maintaining balance throughout a career in neurology.]]>Thu, 13 Aug 2026 15:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/safety-considerations-for-the-first-approved-therapy-in-tk2-deficiencyhttps://www.neurologylive.com/view/safety-considerations-for-the-first-approved-therapy-in-tk2-deficiency<![CDATA[Neurologist Michio Hirano, MD, reviews the safety profile of doxecitine and doxribtimine, discussing common adverse events, dose management strategies, and practical considerations for monitoring patients with TK2 deficiency.]]>Thu, 13 Aug 2026 12:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/first-ever-platform-trial-progressive-supranuclear-palsy-enrolls-inaugural-participanthttps://www.neurologylive.com/view/first-ever-platform-trial-progressive-supranuclear-palsy-enrolls-inaugural-participant<![CDATA[CurePSP and UCSF announced enrollment of the first participant in the PSP Trial Platform, believed to be the first platform trial ever conducted specifically for progressive supranuclear palsy, designed to test multiple investigational drugs simultaneously.]]>Thu, 13 Aug 2026 10:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/how-p-tau217-could-shift-the-timing-alzheimer-carehttps://www.neurologylive.com/view/how-p-tau217-could-shift-the-timing-alzheimer-care<![CDATA[Yogesh Shah, MD, MPH, FAAFP, discusses how earlier identification of Alzheimer pathology with P-tau217 could change the patient journey, from treatment opportunities to long-term planning and dementia risk reduction.]]>Wed, 12 Aug 2026 22:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/post-hoc-analysis-shows-fenfluramine-associated-sustained-seizure-reductions-lgshttps://www.neurologylive.com/view/post-hoc-analysis-shows-fenfluramine-associated-sustained-seizure-reductions-lgs<![CDATA[In a recently published phase 3 post hoc analysis, treatment with fenfluramine was associated with early, sustained reductions in fall-related seizures among patients with Lennox-Gastaut syndrome.]]>Wed, 12 Aug 2026 19:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/ractigen-completes-phase-2-enrollment-for-rag-17-sod1-alshttps://www.neurologylive.com/view/ractigen-completes-phase-2-enrollment-for-rag-17-sod1-als<![CDATA[Ractigen Therapeutics announced completion of enrollment and first dosing across all cohorts of its phase 2 trial of RAG-17, an investigational siRNA therapy for SOD1-mutated ALS, building on phase 1 data recently published in Nature Medicine.]]>Wed, 12 Aug 2026 15:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/what-achieving-an-incat-score-of-0-or-1-means-for-patients-with-cidphttps://www.neurologylive.com/view/what-achieving-an-incat-score-of-0-or-1-means-for-patients-with-cidp<![CDATA[For clinicians treating chronic inflammatory demyelinating polyneuropathy, numerical improvements on disability scales ultimately matter only if they translate into better function for patients.]]>Wed, 12 Aug 2026 12:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/addressing-unmet-needs-adults-spinal-muscular-atrophyhttps://www.neurologylive.com/view/addressing-unmet-needs-adults-spinal-muscular-atrophy<![CDATA[Senda Ajroud-Driss, MD, director of the ALS Clinic at Northwestern Medicine, discussed why adults with spinal muscular atrophy continue to need multidisciplinary care and where the evidence still falls short.]]>Wed, 12 Aug 2026 10:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/building-sustainable-care-plan-for-adolescents-adults-with-lennox-gastaut-syndrome-cynthia-keatorhttps://www.neurologylive.com/view/building-sustainable-care-plan-for-adolescents-adults-with-lennox-gastaut-syndrome-cynthia-keator<![CDATA[The director of neurology at Cook Children's Hospital discusses overlooked challenges in transitioning patients with Lennox-Gastaut syndrome from pediatric to adult care, including insurance changes, mobility concerns, and long-term care planning. [WATCH TIME: 3 minutes]]]>Tue, 11 Aug 2026 22:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/bridging-pediatric-and-adult-care-spinal-muscular-atrophyhttps://www.neurologylive.com/view/bridging-pediatric-and-adult-care-spinal-muscular-atrophy<![CDATA[Divya Jayaraman, MD, PhD, a pediatric neuromuscular specialist at Columbia University Irving Medical Center, discussed the comparative evidence gaps in spinal muscular atrophy and the difficulty of moving patients into adult care.]]>Tue, 11 Aug 2026 19:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/prodromal-msa-criteria-validated-what-new-data-mean-research-clinical-practicehttps://www.neurologylive.com/view/prodromal-msa-criteria-validated-what-new-data-mean-research-clinical-practice<![CDATA[Horacio Kaufmann, MD, Director of the Dysautonomia Center at NYU Langone, discusses the prospective validation of prodromal MSA criteria, how olfactory testing can sharpen specificity, and how close the field is to biomarker-driven early diagnosis.]]>Tue, 11 Aug 2026 15:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/tanruprubart-shows-rapid-responses-first-forward-cohort-guillain-barre-syndromehttps://www.neurologylive.com/view/tanruprubart-shows-rapid-responses-first-forward-cohort-guillain-barre-syndrome<![CDATA[Annexon reported that all 10 patients in the first US and European cohort of its open-label FORWARD study showed rapid, clinically meaningful improvement in strength within days of a single tanruprubart infusion for Guillain-Barré syndrome.]]>Tue, 11 Aug 2026 10:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/building-multidisciplinary-sma-clinic-lessons-from-2-decades-practicehttps://www.neurologylive.com/view/building-multidisciplinary-sma-clinic-lessons-from-2-decades-practice<![CDATA[Sandeep Rana, MD, director of the ALS Center at the Allegheny Health Network Neuroscience Institute, discussed how multidisciplinary clinics are assembled and what still limits access to coordinated care in spinal muscular atrophy.]]>Mon, 10 Aug 2026 19:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/coordinating-multidisciplinary-sma-care-expanding-treatment-landscapehttps://www.neurologylive.com/view/coordinating-multidisciplinary-sma-care-expanding-treatment-landscape<![CDATA[Divya Jayaraman, MD, PhD, a pediatric neuromuscular specialist at Columbia University Irving Medical Center, discussed how multidisciplinary care teams in spinal muscular atrophy are adapting to a growing number of treatment options.]]>Mon, 10 Aug 2026 15:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/this-week-on-neurologylive-august-10-2026https://www.neurologylive.com/view/this-week-on-neurologylive-august-10-2026<![CDATA[Here's some of what is coming soon to NeurologyLive® this week. ]]>Mon, 10 Aug 2026 10:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/fda-approves-oveporexton-nt1-grants-rmat-designation-sasineprocel-pd-emerging-literature-spinal-muscular-atrophyhttps://www.neurologylive.com/view/fda-approves-oveporexton-nt1-grants-rmat-designation-sasineprocel-pd-emerging-literature-spinal-muscular-atrophy<![CDATA[Neurology News Network for the week ending August 8th, 2026. [WATCH TIME: 4 minutes]]]>Sun, 09 Aug 2026 16:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/neurologylive-brain-games-august-9-2026https://www.neurologylive.com/view/neurologylive-brain-games-august-9-2026<![CDATA[Test your neurology knowledge with NeurologyLive®'s weekly quiz series, featuring questions on a variety of clinical and historical neurology topics. This week's topic is Spinal Muscular Atrophy!]]>Sun, 09 Aug 2026 10:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/long-term-follow-up-shows-safety-signal-oxb-102-gene-therapy-parkinsonshttps://www.neurologylive.com/view/long-term-follow-up-shows-safety-signal-oxb-102-gene-therapy-parkinsons<![CDATA[Investigators independently tracked the 6 patients treated in a Parkinson disease gene therapy trial that was abandoned mid-study after its sponsor became insolvent, finding a reassuring safety profile and mixed signals of motor benefit through up to 3 years.]]>Sat, 08 Aug 2026 15:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/pediatrics-to-adulthood-what-lgs-care-transition-still-getting-wronghttps://www.neurologylive.com/view/pediatrics-to-adulthood-what-lgs-care-transition-still-getting-wrong<![CDATA[Cynthia Keator, MD, director of neurology at Cook Children's Hospital, shares her perspective on building longitudinal Lennox-Gastaut syndrome care plans, navigating the pediatric-to-adult transition, and what the field needs to do better for patients and families.]]>Fri, 07 Aug 2026 22:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/neurologylive-friday-5-august-7-2026https://www.neurologylive.com/view/neurologylive-friday-5-august-7-2026<![CDATA[Take 5 minutes to catch up on NeurologyLive®'s highlights from the week ending August 7, 2026. ]]>Fri, 07 Aug 2026 19:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/bezisterim-shows-improvements-motor-nonmotor-symptoms-phase-2-sunrise-pd-trialhttps://www.neurologylive.com/view/bezisterim-shows-improvements-motor-nonmotor-symptoms-phase-2-sunrise-pd-trial<![CDATA[Topline findings from the Phase 2 SUNRISE-PD study showed statistically significant improvements in clinical measures, inflammatory biomarkers, and exploratory neurodegeneration markers among patients with early Parkinson disease treated with bezisterim. ]]>Fri, 07 Aug 2026 17:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articleshttps://www.neurologylive.com/view/episode-172-sma-awareness-month-why-multidisciplinary-care-mattershttps://www.neurologylive.com/view/episode-172-sma-awareness-month-why-multidisciplinary-care-matters<![CDATA[Mind Moments®, a podcast from NeurologyLive®, brings you an exclusive interview with Sandeep Rana, MD. [LISTEN TIME: 15 minutes]]]>Fri, 07 Aug 2026 10:00:00 GMTNeurologyLive - Clinical Neurology News and Neurology Expert InsightsusNeurologyLive - Clinical Neurology News and Neurology Expert Insights Articles