Expert Mike Sharma, MD, explores the scientific rationale for factor XIa inhibition, reviews key clinical trials such as PACIFIC-STROKE and OCEANIC-STROKE, and discusses how emerging therapies like asundexian may redefine secondary stroke prevention by offering safer, more effective antithrombotic strategies beyond aspirin.
Panelist discuss the diagnostic and therapeutic evolution of chronic inflammatory demyelinating polyneuropathy, emphasizing advances in precision diagnostics, patient-centered clinical trial design, and emerging targeted immune-modulating strategies that aim to reduce treatment burden while sustaining long-term disease control.
Fernando Pagan, MD discusses how adjunctive therapies, novel dopamine agonists like tavapadon, advanced levodopa formulations, and subcutaneous infusion pumps are revolutionizing Parkinson's disease treatment by optimizing dopamine levels, reducing motor fluctuations, and minimizing side effects while emerging gene therapies and stem cell treatments offer promising disease-modifying approaches for the future.
CMSC President Jeff Wilken, PhD, interviews expert clinicians across the continuum of multiple sclerosis care daily from the floor of the annual meeting in Phoenix, Arizona.
A panelist discusses how the DORA class of medications offers a novel approach to treating insomnia by selectively targeting orexin receptors to regulate sleep-wake cycles.
An expert discusses the evolving treatment landscape of Duchenne Muscular Dystrophy (DMD), highlighting advances in gene therapy, exon-skipping agents, and novel corticosteroids that aim to slow disease progression, improve muscle function, and enhance quality of life, while emphasizing the growing role of personalized medicine and early intervention in optimizing long-term outcomes.
Panelists discuss how advances in seizure control and termination strategies focus on rapid identification and targeted treatment of seizure types, incorporating newer antiepileptic drugs, rescue therapies, and neuromodulation techniques to improve patient outcomes and prevent progression to status epilepticus.
David Lynch, MD, PhD, discusses how Friedreich ataxia is a progressive neurodegenerative disorder caused by frataxin deficiency, leading to ataxia, cardiac issues, and multisystem complications. Its management requires multidisciplinary care, with recent advances including FDA-approved omaveloxolone and emerging treatments such as vatiquinone and gene therapy offering new hope.
Experts examine the evolving NMOSD treatment landscape, focusing on rituximab's safety concerns, comparative effectiveness of FDA-approved therapies, hospitalization rates, and strategies for optimizing patient outcomes through informed treatment selection and management approaches.
John Michael Schreiber, MD, discusses how genetic testing enhances the diagnosis and management of pediatric epilepsy, emphasizing its importance in tailoring treatment strategies for affected patients.
Stuart Isaacson, MD, discusses how patient-centric, personalized care in Parkinson's Ddisease involves integrating pharmacological therapies with wellness strategies, addressing addresses challenges in delivery, and emphasizing emphasizes the role of advocacy groups in supporting both patients and healthcare providers.
Scott Perry, MD, discusses how Dravet syndrome, a rare genetic epilepsy, presents significant challenges in diagnosis, treatment, and management, emphasizing the importance of early detection, comprehensive care strategies, and support for both patients and caregivers to optimize outcomes and quality of life.
Three medical experts explore key insights on novel treatments for NMOSD, focusing on relapse management, disability accumulation, and the efficacy of new versus traditional therapies.
An in-depth view into treatment and management of type 1 related plexiform neurofibroma across varying patient age ranges is provided by Kaleb Yohay, MD, of NYU Langone Health.
Emma Ciafaloni, MD, provides comprehensive insights on the treatment of Duchenne muscular dystrophy, focusing on diagnostic and treatment practices, ongoing research, and the importance of multidisciplinary care.
CMSC President Jeff Wilken, PhD, interviews expert clinicians across the continuum of multiple sclerosis care daily from the floor of the annual meeting in Nashville, Tennessee.
An expert neurologist discusses the use of wearable devices to aid in symptom diagnosis and management in Parkinson’s Disease (PD).
Dr Lewis gives an in-depth overview of CIDP. He discusses the variants of CIDP, the most common signs and symptoms and the impact of updated CIDP guidelines on clinical practice. Dr. Lewis reviews the current therapeutic landscape and exciting new agents that are on the horizon which could soon add to armamentarium of clinicians treating patients with CIDP.
Dr. Neelam Goyal discusses atypical presentation of myasthenia gravis, her approach to diagnosing and treating myasthenia gravis, and recently approved treatments for it.
An expert neurologist provides insight on Huntington’s disease (HD), highlighting its causes, symptoms, and potential treatments and emerging therapies in development.
Robert Hauser, MD, MBA, discusses the management of OFF episodes and dyskinesia in patients with Parkinson’s disease.
An expert neurologist discusses the use of targeted therapies to personalize treatment for patients with generalized myasthenia gravis (gMG) and reviews the impact on quality of life, the challenges of managing the disease, as well as new and emerging therapies.
Daniel E. Kremens, MD, JD, discusses the impact of OFF episodes on patients with Parkinson’s Disease and the current and newer strategies for managing them.
Nicholas Silvestri, MD, FAAN, discusses myasthenia gravis (MG) and generalized MG (gMG) in the treatment landscape. He reviews current and emerging treatment options and discusses the ADAPT study.
A. Gordon Smith, MD, FAAN, offers perspective on the challenges of diagnosis, new developments in therapeutics, and the need for interdisciplinary collaboration for optimal patient care.
Stuart Isaacson, MD, FAAN discusses how, why, and when OFF episodes manifest in patients with Parkinson’s Disease and highlights current treatments that are available for management of OFF episodes.
Paul Doghramji, MD, FAAFP, provides insight on the use of current treatment modalities for insomnia and the management of sleep disorders in primary care clinics.
