Dementia and Alzheimer Disease

Support, Skepticism, and Statistics: The Aducanumab Saga

After a sudden reversal and complex analyses, aducanumab’s future rests in the hands of the FDA while the community stands split on if the available data are enough to justify an approval.

Compounding Challenges: Conducting Clinical Trials in Alzheimer Disease

Treating Alzheimer disease presents a spiderweb of complexity for physicians, and its intricacies have made assessing therapies equally puzzling.

Episode 24: Aducanumab and Alzheimer Disease Clinical Trials

"Mind Moments," a podcast from NeurologyLive, brings you an exclusive look into the discussion surrounding aducanumab and how it reflects the challenges of conducting clinical trials in Alzheimer disease.

Stem Cell Therapy for TBI: Masahito Kawabori, MD, PhD

January 21, 2021

Video

The associate professor at Hokkaido University and investigator of STEMTRA also discussed other efforts in stroke, Alzheimer disease, and Parkinson disease.

Atrophy Subtypes May Predict Cognitive Decline Patterns, Rates of Conversion to Dementia

January 20, 2021

Article

Hippocampal-sparing and limbic-predominant atrophy were also associated with incident dementia, with faster cognitive decline in the limbic predominant atrophy group.

NeuroVoices: Christian Agudelo, MD, on Sleep’s Impact on Cognitive Decline

January 20, 2021

Article

The Evelyn F. McKnight Neurocognitive Scholar at the University of Miami Miller School of Medicine detailed his study on the correlations between sleep and cognitive decline in middle-aged Hispanics.

ADDF Calls for Global Partnership to Compile Speech Biomarkers in Early Alzheimer

January 19, 2021

Article

New technology enables the collection and analysis of speech behaviors, but this requires an extensive database, which the ADDF seeks to help develop.

FDA Clears First Rapid Traumatic Brain Injury Blood Test

January 19, 2021

Article

Having a blood test available could help eliminate wait time in the emergency room and could reduce the number of unnecessary CT scans by up to 40%, according to Abbott, the test’s developer.

This Week on NeurologyLive — January 18, 2020

January 18, 2021

Article

Here's what is coming soon to NeurologyLive.

Biogen, Apple to Initiate Study to Develop Cognitive Health Digital Biomarkers

January 16, 2021

Article

Maha Radhakrishnan, MD, the Group SVP and chief medical officer at Biogen, discussed the collaborative study between Biogen and Apple that’s expected to kick off later this year.

Donanemab Shows Decline in Alzheimer, Pfizer DMD Study Launched, REM Not Correlated With Seizures

January 16, 2021

Video

Neurology News Network for the week ending January 16, 2021.

NeurologyLive Friday 5 — January 15, 2021

January 15, 2021

Article

Take 5 minutes to catch up on NeurologyLive's highlights from the week ending January 15, 2021.

P-Tau181 Associated With Longitudinal Neurodegeneration in Alzheimer Disease

January 14, 2021

Article

The findings suggest and confirm previous studies that suggested plasma p-tau181 may be used as a measure to monitor Alzheimer disease progression in clinical practice and treatment trials.