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In this segment, Pagan talked about how the field of neurology has changed in the last decade and shared where he sees it moving forward as well.  

Reflecting on the Rapid Evolution of Neurology 

Articles

Roche has updated its phase 3 GENERATION HD2 trial to continue testing only the higher 100 mg dose of tominersen, following interim data favoring its potential clinical benefit in Huntington disease.

GENERATION HD2 Trial of Huntington Agent Tominersen Amended to Include Only Higher Dose

Pagan shared insights from InfusON patient interviews on the challenges and benefits of initiating CSAI therapy and discussed how expert roundtable recommendations can guide neurologists in managing skin nodules associated with treatment. 

Patient Perspectives and Expert Tips on Managing CSAI Challenges in PD 

The switch from 1 anti-CGRP monoclonal antibody to another led to a significant reduction in monthly headache days, regardless of target mechanism, dose history, or time between treatments.

Switching Between Anti-CGRP Monoclonal Antibodies Reduces Headache Days in Non-Responders

Division Chief of Neurology, Dayton Children's Hospital

The division chief of child neurology at Dayton Children’s Hospital discussed findings from a study comparing patient satisfaction scores between telehealth and in-person visits in pediatric epilepsy care. [WATCH TIME: 4 minutes]

Comparable Evidence of Telehealth Benefits vs In-Person Care for Pediatrics: Gogi Kumar, MD

Interim chief executive officer of the Consortium of Multiple Sclerosis Centers.

IJMSC Insights offers a closer look at the latest research and the people behind it from the community of the International Journal of Multiple Sclerosis Care (IJMSC) and the Consortium of Multiple Sclerosis Centers (CMSC).

IJMSC Insights: Kathleen Costello, Interim CEO of CMSC

The neuroradiologist at Mayo Clinic discussed the clinical and conceptual differences between Alzheimer disease diagnostic frameworks and how clinicians should prepare for a shifting treatment landscape. [WATCH TIME: 4 minutes]

Rethinking Alzheimer Diagnosis and Disease Staging: Clifford Jack, MD

Resident in the Department of Neurology at NYU Langone Health.

The resident in the Department of Neurology at NYU Langone Health discussed the preliminary findings of a 9-month study on lecanemab recently presented at the 2025 AAN Annual Meeting. [WATCH TIME: 2 minutes]

Evaluating Safety and Early Outcomes of Lecanemab Treatment for Alzheimer Disease: Philip Kuball, MD

NeurologyLive is your direct connection to the latest neurology news and interviews with expert neurologists in multimedia formats.

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James F. Howard Jr, MD, FAAN; Nicholas J. Silvestri, MD, FAAN

Burst Expert Illustrations & Commentary™: Visualizing the Role of FcRN in Neurological Disorders

BURST Expert Illustrations and Commentaries™: Visualizing FcRn as a Therapeutic Target in Neurological Disease

BURST Expert Illustrations and Commentaries™: Visualizing the Implications of FcRN-Targeted Therapies on Generalized Myasthenia Gravis

Nicholas J. Silvestri, MD, FAAN; Neelam Goyal, MD

Clinical Consultations™: Navigating the Evolving Treatment Landscape in Generalized Myasthenia Gravis

Burst Expert Illustrations & Commentary™: Visualizing the Role of Subcutaneous Infusion as an Alternate Administration Route for Medical Interventions

Dani Cabral, MD; Marwan N. Sabbagh, MD, FAAN, FANA

SimulatED™: Diagnosing and Treating Alzheimer’s Disease in the Modern Era

SimulatED™: Understanding the Role of Genetic Testing in Patient Selection for Anti-Amyloid Therapy

Sanjai Rao, MD, DFAPA; Jonathan M. Meyer, MD

Expert Illustrations & Commentaries™: New Targets for Treatment in Cognitive Impairment in Schizophrenia – The Role of NMDA Receptors and Co-agonists

BURST CME™ Part I: Understanding the Impact of Huntington’s Disease

Burst CME™ Part II: The Evolving Treatment Landscape for Huntington Disease

Carolina Neuromuscular Disease Summit

SimulatEd™ From Discomfort to Relief: Acute Pain Management Essentials

Alireza Atri, MD, PhD; Erik S. Musiek, MD, PhD; Malú Gámez Tansey, PhD


Evolving Perspectives in Alzheimer's Disease: Reaching an Earlier Diagnosis, Understanding Neuroinflammation, and Exploring Therapeutic Advances

Daniel Claassen, MD, MS; Martha A. Nance, MD

 Clinical ShowCase: Developing a Personalized Treatment Plan for a Patient with Huntington’s Disease Associated Chorea

Carrie M. Hersh, DO, MSc, FAAN; Anna Shah, MD

Medical Crossfire®: Integrating Real-World Data to Improve Outcomes for Patients With Multiple Sclerosis

James F. Howard Jr, MD; Nicholas J. Silvestri, MD, FAAN; Neelam Goyal, MD

Medical Crossfire® - Optimizing Management for Patients With Generalized Myasthenia Gravis: Focus on Complement Inhibitors

Jessica Ailani, MD, FAHS, FAAN; Paul G. Mathew, MD, DNBPAS, FAAN, FAHS

Burst CME™: Setting the Stage – Individualizing Migraine Care for Diverse Populations Across Care Settings

Burst CME™: The Patient Journey – Unmet Needs From Diagnosis Through Management of Migraine

Alireza Atri, MD, PhD; Erik S. Musiek, MD, PhD; Malú Gámez Tansey, PhD

 Evolving Perspectives in Alzheimer Disease : Reaching an Earlier Diagnosis, Understanding Neuroinflammation, and Exploring Therapeutic Advances

Burst CME™: Optimizing the Use of CGRP Targeted Agents for the Treatment of Migraine

Burst CME™: Optimizing Migraine Management – Addressing Unmet Needs, Individualizing Care for Diverse Populations, and Utilizing CGRP Targeted Agents

Ilan Melnick, MD; Alejandro Alva, MD; Linda Trinh, DNP, PMHNP, FNP, MPH

Community Practice Connections™: Optimizing the Management of Tardive Dyskinesia—Addressing the Complexity of Care With Targeted Treatment

Paul G. Auwaerter, MD, MBA; Paul P. Doghramji, MD, FAAFP; Aruna Subramanian, MD

Cases and Conversations™: Applying Best Practices to Prevent Shingles in Your Practice

John F. Brandsema, MD; Abigail N. Schwaede, MD; Samuel J. Mackenzie, MD, PhD

Patient, Provider, and Caregiver Connection™: Pediatric Myasthenia Gravis—Current Treatment and Emerging Concepts

Mind Moments™: Optimizing Management for Patients with Generalized Myasthenia Gravis

Cases and Conversations™: Navigating the Complexities of Managing Myasthenia Gravis in Pediatric and Pregnant Patient Populations

John Brandsema, MD; Carla D. Zingariello, DO

Cases and Conversations™: Little Voices, Big Challenges – Comprehensive Care for Pediatric Spinal Muscular Atrophy

Jeffrey A. Allen, MD; Karissa L. Gable, MD

Identifying and Treating CIDP in the Modern Era

Estelamari Rodriguez, MD, MPH; Millie Das, MD; Ruham Nasany, MD

A Breath of Strength: Managing Cancer Associated LEMS and Lung Cancer as One

Anne Chiang, MD, PhD; J. Douglas Miles, MD, PhD, FAAN; Suma Satti, MD

Striking the Right Nerve: Managing Cancer Associated LEMS in Lung Cancer Patients

Abigail N. Schwaede, MD; Emmanuelle (Noelle) Tiongson, MD

Patient, Provider, and Caregiver Connection: Improving Diagnosis and Care for Adolescent Myasthenia Gravis Patients – A New Frontier

Shamik Bhattacharyya, MD, MS, FAAN; Mirla Avila, MD; Dean Wingerchuk, MD

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