Latest Conference Coverage

Expanding Diagnostic Tools for iRBD Through Actigraphy-Based Classifiers

Emmanuel During, MD, an associate professor of neurology at the Icahn School of Medicine at Mount Sinai, discussed the external validation of an actigraphy-based classifier for diagnosing iRBD and its implications for scalable neurodegenerative screening.

Real-World Data Highlight Patient-Reported Benefits of Intranasal Zavegepant for Acute Migraine

Patients using intranasal zavegepant for acute migraines report significant pain relief and improved daily functioning, highlighting its real-world effectiveness.

Exploring Tools to Target the Glymphatic System and Alzheimer Disease Risk: Andrew Varga, MD

The associate professor of medicine at the Icahn School of Medicine at Mount Sinai outlined emerging interventions aimed at enhancing glymphatic clearance to potentially lower Alzheimer disease risk. [WATCH TIME: 4 minutes]

Late-Breaking Phase 2b PARADIGM Data Support Continued Development of PrimeC in ALS

Recently reported phase 2b results revealed that PrimeC consistently altered ALS-related miRNA expression, reinforcing its potential as a multi-targeted therapy and aligning with previously reported clinical benefits.

Centering Empathy in Parkinson Care by Listening Beyond the Diagnosis: María L. De León, MD

The movement disorder specialist and patient living with Parkinson disease highlighted the need for a more human-centered approach in managing chronic and progressive movement disorders. [WATCH TIME: 6 minutes]

Using Veterans Health Data to Gain Insights on Sex Differences in Migraine and Stroke Risk: Elizabeth Seng, PhD

The professor of neurology at Albert Einstein College of Medicine talked about new findings presented at AHS, which suggested that both men and women with migraine can face significantly increased risks of ischemic stroke. [WATCH TIME: 5 minutes]

Advancing Research for Cognitive Behavioral Therapy to Treat Nightmares: Lisa Cromer, PhD

The professor of psychology at the University of Tulsa discussed the clinical utility of using CBT to treat nightmares–especially in children with comorbid conditions like ADHD and anxiety–and the latest research her lab is conducting. [WATCH TIME: 4 minutes]

Assessing Eptinezumab’s Impact in Reducing Migraine Burden Through Longer Interictal Periods: Amaal Starling, MD, FAHS, FAAN

The associate professor of neurology at Mayo Clinic College of Medicine discussed findings presented at AHS 2025 from a post hoc analysis of the phase 3b DELIVER study testing eptinezumab in patients with migraine. [WATCH TIME: 5 minutes]

Episode 145: Rewiring Stroke Recovery: What the Glymphatic System Can Teach Us

Mind Moments®, a podcast from NeurologyLive®, brings you an exclusive interview with Joyce Lee-Iannotti, MD, PhD. [LISTEN TIME: 17 minutes]

Gender Disparities in Mood and Quality of Life of Parkinson Disease After DBS: Molly Abbott, BM BCh

The neuropsychiatry researcher at King's College London highlighted significant gender differences in anxiety, depression, quality of life, and social support among patients with PD undergoing deep brain stimulation. [WATCH TIME: 5 minutes]

Myasthenia Gravis Medication Nipocalimab Outperforms FcRn Blockers in Indirect Comparison Analysis

Indirect treatment comparisons showed significantly greater or statistically higher improvements in MG-ADL scores with nipocalimab versus other FcRn blockers over 24 weeks.

Gastrointestinal Involvement in Parkinson Disease and Its Impact on Levodopa Efficacy: Laren Becker, MD, PhD

The assistant professor of medicine at Stanford University highlighted how gastrointestinal dysfunction in Parkinson disease can affect levodopa bioavailability and symptom management. [WATCH TIME: 7 minutes]

Oscillations in Non-REM Sleep Offer New Insight Into Alzheimer Disease Biology: Bryce Mander, PhD

The associate professor of psychiatry and human behavior at UC Irvine explored how analyzing specific sleep oscillations may uncover early neurodegenerative changes and guide future therapeutic targets. [WATCH TIME: 4 minutes]

Why Early Identification of Atypical Parkinsonian Syndromes Matters in the Clinic: David Shprecher, DO, MSci, FAAN

The director of movement disorders at the Banner Sun Health Research Institute discussed distinguishing atypical Parkinsonian disorders early and planning care around their complex symptomatology. [WATCH TIME: 4 minutes]

NeuroVoices: Kumar Budur, MD, MS, on BP1.15205 as a Next-Gen Therapy for Narcolepsy

The chief medical and scientific officer at Harmony Biosciences discussed the pharmacologic rationale and preclinical development of BP1.15205, a novel orexin receptor 2 agonist for hypersomnolence.

SUNRISE Trial Confirms Effectiveness of Eptinezumab in Asian Population With Chronic Migraine

Eptinezumab showed significant efficacy in reducing chronic migraine days in Asian patients, potentially addressing a critical unmet need for effective treatments.

Advancing Research and Drug Development for Isolated RBD: Emmanuel During, MD

The associate professor of neurology at the Icahn School of Medicine at Mount Sinai detailed how monitoring tools and neuroprotective approaches are evolving for iRBD as research intensifies on its link to Parkinsonian syndromes. [WATCH TIME: 4 minutes]

Recognizing Gastrointestinal Symptoms as Early Indicators of Parkinson Disease

Laren Becker, MD, PhD, a physician-scientist at Stanford University, discussed how gastrointestinal dysfunction and peripheral dopaminergic activity impact Parkinson disease treatment and progression.

Reduction in Parkinson OFF Episodes Through Subcutaneous Apomorphine Infusion Leads to Doubling of Good ON Time

Continuous subcutaneous apomorphine infusion significantly reduces OFF episodes and enhances ON time in Parkinson's disease patients, improving overall health status.

Revisiting Deep Brain Stimulation in a Pediatric-Onset Dystonia Case: Pamela Zeilman, NP

The nurse practitioner in the Center for Movement Disorders & Neurorestoration at the University of Florida discussed a complex case of childhood-onset dystonia treated with DBS. [WATCH TIME: 6 minutes]

Switch From Amantadine Immediate-Release to Gocovri Results in Improved Real-World Parkinson Disease Benefits

Research reveals that delayed-release amantadine significantly reduces Parkinson disease symptoms and medication use, offering patients improved quality of life.

Post Hoc Analysis Highlights Brexpiprazole’s Efficacy and Tolerability in Alzheimer Agitation

As the first FDA-approved treatment for Alzheimer agitation, brexpiprazole showcased effective symptom relief with a favorable safety profile.

Validating a Wearable-Based Classifier to Detect iRBD: Emmanuel During, MD

The associate professor of neurology at the Icahn School of Medicine at Mount Sinai explained how his team validated an iRBD actigraphy classifier across new devices and datasets to enhance early, scalable screening for neurodegenerative disease. [WATCH TIME: 5 minutes]

Targeting Sleep and the Glymphatic Pathway to Improve Stroke Rehabilitation Outcomes: Joyce Lee-Iannotti, MD, FAAN, FAASM

The sleep and stroke neurologist at Barrow Neurological Institute provided insights on the potential of sleep-boosting strategies—including pharmacologic options—to enhance glymphatic clearance and improve stroke recovery outcomes. [WATCH TIME: 4 minutes]

NeuroVoices: Cheryl Kyinn, PA-C, on Personalizing On-Demand Therapies for OFF Episodes in Parkinson Disease

A physician assistant specializing in Parkinson disease shared key clinical considerations for selecting and educating patients about on-demand therapies for the movement disorder.

Sharing Treatment Strategies for Patients With Parkinson Disease Beyond Medication: Esther Labib-Kiyarash, MSHA, CPHQ

At ATMRD 2025, a patient advocate living with PD and advisory board member of the Parkinson's Foundation outlined key nonpharmacologic tools that have supported her care journey. [WATCH TIME: 5 minutes]

Increased Awareness for Essential Tremor Treatment, MR-guided Focused Ultrasound: Justin Martello, MD

The neurologist at Christiana Care discussed how focused ultrasound may be emerging as a preferred, less invasive treatment option for essential tremor, especially in older patients with comorbidities. [WATCH TIME: 5 minutes]

Understanding the Phenomenology and Impact of Psychosis in Parkinson Disease: William Ondo, MD

The director of the Movement Disorders Clinic at Houston Methodist Hospital discussed the distinct features, progression, and clinical implications of psychosis in Parkinson disease. [WATCH TIME: 4 minutes]

Incorporating Palliative Care Principles into Movement Disorder Management: Jennifer Corcoran, MD

The movement disorder neurologist at University of Rochester Medical Center outlined a 5-pillar model that emphasized holistic care, patient-centered communication, and proactive support in movement disorders. [WATCH TIME: 5 minutes]

Improving the Management of Parkinson Through Psychological Interventions: Marcia Pasqualini, PhD

The professor of psychology at Avila University discussed how cognitive behavioral therapy and social support can help to improve quality of life for individuals with Parkinson disease. [WATCH TIME: 4 minutes]