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Phase 3 Trial of Cenobamate Assesses Therapy for Primary Generalized Tonic-Clonic Seizures

Dystrophin Pathway and Treatments Offer Hope for Patients with Duchenne Muscular Dystrophy

Investigators Unlock New Targets in Obstructive Sleep Apnea

Remyelination in Multiple Sclerosis: The Next Treatment Frontier

Telestroke Offers Opportunities, But Challenges Persist

Genetics Fuel Parkinson Pipeline Growth

Comment from Jeffrey Cummings, MD, ScD

Challenges and Excitement in Alzheimer Disease

The director of the Center for Neurodegeneration and Translational Neuroscience and director emeritus, Cleveland Clinic Lou Ruvo Center for Brain Health, shared thoughts on his hope for the future of Alzheimer disease, among other topics.

Costantino Iadecola, MD: Cognitive Reserve in Alzheimer Disease

The Anne Parrish Titzell Professor of Neurology and Neuroscience at Weill Cornell Medicine’s Feil Family Brain and Mind Research Institute discussed how to make the decision about who will end developing Alzheimer and who will not when amyloid buildup occurs.

Study Suggests No Significant Next-Morning Driving Impairment with Lemborexant

Overall, there were no statistically significant or clinically relevant effects of bedtime administration of lemborexant on next-morning driving performance in healthy adult and elderly volunteers.

FDA Provides Feedback for Reldesemtiv Clinical Trial End Points in SMA

The regulatory agency has informed Cytokinetics that the use of the 6-minute walk test will be an acceptable efficacy outcome measure for the skeletal muscle troponin activator.

FDA Clears IND for Huntington Disease Therapy AMT-130

A planned phase 1/2 trial of the recombinant AAV5 vector treatment is expected to begin dosing patients in the second half of 2019.

Claudia Testa, MD, PhD: Pairing Huntington Disease Treatments

Jessica Ailani, MD: Understanding the Biology of Migraine

William Tatum, DO: When to Obtain a Routine EEG While Managing a Patient with Epilepsy