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Top Medical News

FDA Extends Review of Omaveloxolone in Friedreich Ataxia

August 09, 2022

By Matt Hoffman

After Reata Pharmaceuticals submitted an analysis from the MOXIe extension study of the investigational agent as part of the NDA submission, the FDA extended the PDUFA date to February 2023.

Pepinemab’s Upregulation of SEMA4D Expression Warrants Further Development in Huntington, Alzheimer Disease

August 09, 2022

By Marco Meglio

In a phase 2 trial, pepinemab significantly improved metabolic activity as detected by FDG-PET in the majority of brain regions examined, as well as correlated with changes in cognition across both Huntington disease and Alzheimer disease.

Future Relapse Remission in Multiple Sclerosis Impacted by Retinal Layer Thinning

August 09, 2022

By Marco Meglio

The impact of retinal thinning was higher when using GCIPL rather than pRNFL thinning as it explained more of the variance in relapse remission.

Delayed Diagnosis of Functional Seizures Associated With Abnormal Processing of Face Emotions

August 09, 2022

By Marco Meglio

Increased posterior cingulate cortex activation to sad faces in the long-delay diagnostic group were associated with worse symptoms of depression, as expressed by Beck Depression Inventory scores.

Migraine and Mental Health: Taking Time to Ask the Questions

August 08, 2022

By Matt Hoffman

Lawrence Newman, MD, offered his insight into the findings of a survey conducted by the American Headache Foundation that identified correlations between migraine and mental health conditions.

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