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Top Medical News

Diabetes Linked With Increased Levels of Neurofilament Light, Neuroaxonal Damage in Parkinson Disease

August 10, 2022

By Marco Meglio

Investigators identified increased levels of neurofilament light that corresponded significantly with patients’ diabetic status, even after adjustment for age, BMI, and vascular risk factors.

NeuroVoices: Vesna Garovic, MD, PhD, on Severe Preclampsia’s Effect on Late-Life Cognition, Neuroinflammation for Women

August 10, 2022

By Marco Meglio

The chair of the nephrology division at Mayo Clinic provided context on new findings on the risks of preeclampsia, a hypertensive disorder, and elevated levels of neuroinflammation and neurovascular damage.

FDA Extends Review of Omaveloxolone in Friedreich Ataxia

August 09, 2022

By Matt Hoffman

After Reata Pharmaceuticals submitted an analysis from the MOXIe extension study of the investigational agent as part of the NDA submission, the FDA extended the PDUFA date to February 2023.

Pepinemab’s Upregulation of SEMA4D Expression Warrants Further Development in Huntington, Alzheimer Disease

August 09, 2022

By Marco Meglio

In a phase 2 trial, pepinemab significantly improved metabolic activity as detected by FDG-PET in the majority of brain regions examined, as well as correlated with changes in cognition across both Huntington disease and Alzheimer disease.

Future Relapse Remission in Multiple Sclerosis Impacted by Retinal Layer Thinning

August 09, 2022

By Marco Meglio

The impact of retinal thinning was higher when using GCIPL rather than pRNFL thinning as it explained more of the variance in relapse remission.

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