Early Identification and Management of Multiple Sclerosis in Pediatric Patients

Recommendations to health care professionals in the community who play a role in managing pediatric patients with multiple sclerosis and considerations for improving how the condition is managed.

An overview of therapies under investigation in pediatric multiple sclerosis.

Drs Brenda L. Banwell and Lauren B. Krupp highlight current unmet needs regarding the treatment and management of patients with pediatric onset multiple sclerosis.

Experts who treat patients with multiple sclerosis react to the availability of oral fingolimod for pediatric patients and highlight considerations for utilizing the therapy in practice.

An overview of fingolimod for patients with relapsing pediatric multiple sclerosis based on the PARADIGMS trial and the FDA’s breakthrough therapy designation of the oral therapy for appropriate patients.

Drs Brenda L. Banwell and Lauren B. Krupp review the design and outcomes of the PARADIGMS trial with fingolimod in pediatric patients with multiple sclerosis.

Recommendations for selecting therapy in patients with pediatric multiple sclerosis and monitoring treatment response.

A historical perspective on the treatment of pediatric multiple sclerosis.

Health care professionals who may play a role in caring for patients with pediatric multiple sclerosis and support groups that are available to address patient and caregiver needs.

Recommendations for navigating through the challenges associated with treating and caring for patients with pediatric multiple sclerosis.

An overview of treatment guidelines and recommendations for managing patients with pediatric multiple sclerosis.

Criteria and strategies used to help clinicians accurately diagnose multiple sclerosis in pediatric patients.

Symptoms that young patients with multiple sclerosis commonly present with, and recommendations for accurately diagnosing the condition in the pediatric population.

The current prevalence of multiple sclerosis in pediatrics and an overview of various ways for which the condition may present in patients.

Lauren B. Krupp, MD, discusses the underlying biology of multiple sclerosis (MS) and remarks on Epstein-Barr viral exposure as a risk factor for pediatric MS.
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