The NeurologyLive® Migraine Disease Spotlight page offers specific updates and coverage on the latest expert conversations and data readouts related to the treatment and management of patients with migraine disorders.
August 27th 2025
In a recent study, investigators developed multireceptor antagonist peptides that could block CGRP and PACAP, providing proof-of-concept for a potential new approach to targeting pathways involved in migraine.
Using AI to Assist in Identifying Cardiovascular Risk in Patients With Migraine
June 26th 2025Chia-Chun Chiang, MD, associate professor of neurology at Mayo Clinic Rochester, discussed how AI-based ECG and imaging tools can aid in predicting stroke and cardiovascular outcomes in patients with migraine.
Patients Voicing Key Needs for Migraine Care and Advocacy: Elizabeth W. Leroux, MD, FRCPC
June 24th 2025The neurologist and headache specialist at the Montreal Neurological Clinic spoke about a recent national survey presented at AHS 2025 that revealed insightful patient perspectives in migraine. [WATCH TIME: 5 minutes]
Exploring Cognitive Difficulties in Migraine: Aligning Subjective and Objective Findings
June 22nd 2025Laura Sebrow, PhD, a post doctoral neuropsychology fellow at North Shore University Hospital, discussed the relationship between patients’ reported cognitive difficulties and measurable cognitive performance during different migraine phases.
Targeting A3AR in Trigeminal Neuropathic Pain: A Promising Approach for an Unmet Clinical Need
June 21st 2025Marcela Romero-Reyes, DDS, PhD, FAHS, director of the Brotman Facial Pain Clinic at the University of Maryland, discussed a promising and potentially safer therapeutic approach for managing trigeminal neuropathic pain.
Rolling Out CT-132 Lessons and Opportunities in Migraine Care: Stewart Tepper, MD
April 29th 2025The professor of neurology at the Geisel School of Medicine at Dartmouth discussed the clinical rollout of CT-132, a newly FDA-approved digital therapeutic for migraine, and the educational needs facing the neurology community. [WATCH TIME: 4 minutes]
Large Danish Cohort Study Reveals No Significant Association Between HLA Alleles and Migraine
April 16th 2025Although the study reported no evidence linking human leukocyte antigen alleles to migraine, the findings were not replicated, suggesting the HLA system may not be involved in migraine susceptibility.
CGRP Therapies as Potential First-Line Migraine Preventive Treatment: Andrew Charles, MD
April 7th 2025The director of the UCLA Goldberg Migraine Program discussed the advantages, evidence base, and evolving payor support for CGRP-targeting therapies as potentially a first-line option in migraine prevention. [WATCH TIME: 5 minutes]
Ubrogepant During Migraine Prodrome Shows Significant Benefits in Patient-Reported Outcomes
March 31st 2025A recent analysis of the PRODROME trial explored the impact of ubrogepant, an FDA-approved acute treatment of migraine with or without aura, on patient-reported outcomes in migraine management.
Mixed Bruxism Episodes More Common in Migraine and Temporomandibular Disorders, Study Finds
March 30th 2025A recent case-control study suggests that although sleep bruxism may not be directly associated with migraine in patients with temporomandibular disorders, mixed bruxism episodes occur more frequently in those with migraine.
Misdiagnosed Migraine Leads to Significant Burden on Healthcare Resource Utilization
March 13th 2025New research highlights the significant economic burden of misdiagnosed migraine patients, revealing higher healthcare costs and resource utilization over time compared to those with accurate diagnoses.
Kinetic Oscillation Stimulation Proves to be Therapeutically Beneficial for Chronic Migraine
March 11th 2025Treatment with the Chordate System led to a significantly greater reduction in monthly headache days during the performance assessment period, with a reduction of 3.5 days compared to 1.2 days in the sham group.