Insights

  

Advances in the Management of Relapsing Multiple Sclerosis


Robert J. Fox, MD, explains what is currently known about the underlying biology of multiple sclerosis and highlights potential risk factors that may predispose a patient to develop the condition.

As more becomes understood about the etiology of multiple sclerosis, subtypes of multiple sclerosis have been further characterized and redefined.

Drs Robert J. Fox and Fred D. Lublin review the most recent diagnostic criteria in multiple sclerosis, highlighting changes to the McDonald criteria and their impact on clinical practice.

The evolving role of magnetic resonance imaging in the diagnosis of multiple sclerosis as well as its use to monitor disease activity and guide treatment decisions.

As therapy continues to evolve in multiple sclerosis, experts highlight key considerations for selecting an appropriate treatment option and counseling patients on overall goals of therapy.

First-line treatment options in multiple sclerosis and recommendations to help clinicians make appropriate, individualized treatment decisions.

Experts comment on the results of the phase 3 EXPAND study of siponimod in secondary progressive multiple sclerosis and explore the treatment’s safety versus efficacy in clinical practice.

Recommendations for utilizing ocrelizumab for the treatment of relapsing multiple sclerosis (MS) and primary progressive MS based on the most current clinical trial data.

Implications for using cladribine or diroximel fumarate as therapy for relapsing multiple sclerosis, as well as considerations for selecting an appropriate dose of fingolimod. 

Strategies used to monitor patients for treatment response and/or disease progression, and factors that impact clinicians’ decisions to switch to a different therapy for relapsing disease.

Progress in the treatment of patients with multiple sclerosis. 

Drs Robert J. Fox and Fred D. Lublin conclude a discussion on the management of relapsing multiple sclerosis by highlighting best practices in community settings to better optimize care for patients. 
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