SLEEP

Pitolisant Shows No Cardiac Safety Signals in Narcolepsy

September 04, 2020

Despite previous literature documenting cardiovascular disease comorbidity in patients with narcolepsy, pitolisant treatment did not demonstrate any cardiac safety signals.

Solriamfetol Improves Excessive Daytime Sleepiness and Driving Performance Ability

September 01, 2020

The FDA-approved agent showed significant impact in decreasing standard deviation of lateral position, a measure used to assess driving performance.

Pitolisant Improves Daytime Sleepiness and Cataplexy in Severely Burdened Patients

September 01, 2020

Pooled data from 2 clinical trials of the H3-receptor antagonist/inverse agonist show it improved cataplexy and excessive daytime sleepiness in patients with narcolepsy who were most hampered by symptoms.

Lemborexant Demonstrates Efficacy in Elders

September 01, 2020

Already FDA approved for the treatment of insomnia in adults, lemborexant’s ability to improve sleep outcomes in the elderly was highlighted in a study presented at SLEEP 2020.

Lemborexant Improves Sleep Outcomes Following Placebo Randomization Switch

August 27, 2020

Benefit from lemborexant was evident after 1 month of switching from placebo to the active treatment and was sustained through the entirety of the 12-month trial.

Cognitive Behavioral Therapy for Insomnia Shows Multiple Benefits for Women

August 27, 2020

Multiple abstracts at SLEEP 2020 show CBT-I’s success in aiding women with insomnia, including those going through pregnancy, and those who are veterans both with and without PTSD.