Clinical Focus

Video Series

Publications

Current Issue

Eight Ways to Evaluate a Telehealth Vendor

Adapting Neurological Care Amid COVID-19

Stroke Care Evolves During These Uncertain Times

Verdiperstat Aims to Be First DMT for Multiple System Atrophy

Targeting Bruton Tyrosine Kinase for Multiple Sclerosis Treatment

Managing Narcolepsy and Excessive Daytime Sleepiness

Treating Medication Overuse Headache: Opportunities for Improvement

Peer Exchange

Advances in Early Treatment Approaches in Multiple Sclerosis

EPISODE 1 : Updated McDonald Criteria for Diagnosing MS

Fred D. Lublin, MD leads a discussion on the 2017 revisions to the McDonald criteria to diagnose multiple sclerosis.

EPISODE 2 : Diagnostic Work-Up for MS

Key opinion leaders discuss red flags in making a multiple sclerosis diagnosis and the possibility for misdiagnosis.

EPISODE 3 : MRI in the Diagnosis of MS

Expert neurologists outline how the use of MRI has changed the diagnosis of multiple sclerosis and the importance of standardized protocols.

EPISODE 4 : Clinical Courses in MS

Fred D. Lublin, MD, outlines the 4 clinical courses in multiple sclerosis and that they must be framed in time.

EPISODE 5 : Modern Conversion Rate to Secondary MS

The decrease of the modern conversion rate to secondary progressive disease is discussed as well as the importance of a wellness program.

EPISODE 6 : Importance of Early Treatment of MS

Panelists discuss the importance and value of early identification and treatment of multiple sclerosis.

EPISODE 7 : Choosing Initial Therapy for Treatment of MS

Key opinion leaders agree there is no consensus on choosing initial therapy for treatment of multiple sclerosis.

EPISODE 8 : Factors to Consider for First-Line Therapy for MS

Panelists agree there is no treatment algorithm when starting therapy for multiple sclerosis but discuss some factors to consider when choosing therapy.

EPISODE 9 : Recent Treatment Strategies Explored for Relapsing MS

Implications for using cladribine or diroximel fumarate as therapy for relapsing multiple sclerosis, as well as considerations for selecting an appropriate dose of fingolimod.

EPISODE 10 : ASSESS Clinical Trial of Fingolimod for Treatment of MS

Stephen C. Krieger, MD, outlines the ASSESS clinical trial of the orally administered S1P receptor modulator fingolimod.

EPISODE 11 : Addressing Limitations in the Management of MS

Progress in the treatment of patients with multiple sclerosis.

EPISODE 12 : EXPAND Clinical Trial of Siponimod for Treatment of MS

A discussion of the EXPAND phase III clinical trial of the selective S1P receptor modulator siponimod for treatment of multiple sclerosis.

EPISODE 13 : Patient Selection for Alemtuzumab for Treatment of MS

Panelists debate the use of alemtuzumab in multiple sclerosis, weighing the high efficacy vs the high frequency of autoimmune complications and serious adverse events.

EPISODE 14 : Recent Approvals for MS: Cladribine and Diroximel Fumarate

The panel outlines data from the phase 3 ORACLE MS and CLARITY extension trials of cladribine and the phase 3 EVOLVE-MS-2 trial of these 2 drugs recently FDA approved for multiple sclerosis.

EPISODE 15 : Review of Natalizumab for MS

Key opinion leaders discuss the use of natalizumab for multiple sclerosis and the JCV antibody blood test to determine risk of developing PML.

EPISODE 16 : Original Drugs to Treat MS

Expert neurologists offer opinions on some of the original drugs to treat multiple sclerosis, including interferon and glatiramer acetate.

EPISODE 17 : Drugs in Development for MS, Including Ofatumumab

A discussion of some drugs in development for multiple sclerosis, including the ASCLEPIOS I and II phase 3 trials of ofatumumab.

EPISODE 18 : Unmet Needs and Final Thoughts on Treating MS

Panelists wrap up their discussion on multiple sclerosis by identifying areas of unmet needs and offering advice to community-based neurologists.