Samuel Pleasure, MD, PhD

August 13, 2015

Observations over the last few years have indicated that an inciting event of narcolepsy may be infection with influenza or vaccination with particular influenza vaccines.

July 09, 2015

Our blogger discusses a recent study investigating the likelihood of head trauma in older patients leading to the onset of Parkinson disease and the implications of the findings.

June 01, 2015

What is the function of continued adult myelination in the normal undiseased brain? A recent study sheds remarkable light on this process and its importance.

April 28, 2015

Potential approaches to devising strategies that may allow amelioration of this disease are revealed in a recent study. But questions remain.

March 31, 2015

A switch to a second-line drug in a patient receiving first-line therapies likely will be effective at decreasing disease activity.

February 24, 2015

The ultimate cause is found in only about half of patients, so improved understanding of the prognostic and diagnostic features is of high priority.

January 28, 2015

The risk of progressive multifocal leukoencephalopathy in patients receiving Tysabri for MS is a concern about this otherwise extremely effective therapy.

December 17, 2014

What happens before the demyelinating lesions of MS appear? Does smoking confer protection against Parkinson disease? How is NMDA receptor-associated disease reversed? Here are 4 fine papers from 2014 that set out to answer these questions.

November 04, 2014

Patients with juvenile myoclonic epilepsy appear to have modest cognitive defects and imaging abnormalities early on that are unlikely to be associated with anti-epileptic therapy. This is a clear departure from traditional teaching.

October 02, 2014

Serum testing for NMDAR and other autoantibodies is fraught with pitfalls, and careful clinical consideration is important.