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Samuel Pleasure, MD, PhD



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Head Trauma and the Risk of Parkinson Disease

July 09, 2015

Our blogger discusses a recent study investigating the likelihood of head trauma in older patients leading to the onset of Parkinson disease and the implications of the findings.

Myelin Formation and Motor Learning in Adulthood

June 01, 2015

What is the function of continued adult myelination in the normal undiseased brain? A recent study sheds remarkable light on this process and its importance.

Drug Switching in Active Relapsing Remitting MS

March 31, 2015

A switch to a second-line drug in a patient receiving first-line therapies likely will be effective at decreasing disease activity.

4 Exciting Neurology Papers from 2014

December 17, 2014

What happens before the demyelinating lesions of MS appear? Does smoking confer protection against Parkinson disease? How is NMDA receptor-associated disease reversed? Here are 4 fine papers from 2014 that set out to answer these questions.

Idiopathic Primary Generalized Epilepsies: Benign?

November 04, 2014

Patients with juvenile myoclonic epilepsy appear to have modest cognitive defects and imaging abnormalities early on that are unlikely to be associated with anti-epileptic therapy. This is a clear departure from traditional teaching.

Tests for Autoantibodies in Brain Disease Raise Questions

October 02, 2014

Serum testing for NMDAR and other autoantibodies is fraught with pitfalls, and careful clinical consideration is important.