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Ideal Patient Profiles for Spinal Muscular Atrophy Therapies / Perfis ideais de pacientes para tratamento da atrofia muscular espinhalThe expert panel comments on ideal patient profiles for SMA treatment with nusinersen, onasemnogene abeparvovec, and risdiplam. O painel de especialistas comenta os perfis ideais de pacientes para tratamento da atrofia muscular espinhal com nusinersena, onasemnogeno abeparvoveque e risdiplam.
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Stanford Children’s Health: A Comprehensive Approach to Care for a Child With a Neurological ConditionPhysicians from Stanford Children’s Health offer their keys to successful pediatric neuroscience teams and what to focus on to provide a better quality of life for children.
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Uncovering New, Synergistic Ways to Treat Tuberous Sclerosis Complex: Darcy Krueger, MD, PhDThe director of the Tuberous Sclerosis Clinic at Cincinnati Children’s provided insight on whether the timing and combination of certain therapeutics may impact the long-term care for patients with tuberous sclerosis complex. [WATCH TIME: 3 minutes]
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Understanding the Association Between Obstructive Sleep Apnea Treatment and Dementia Risk: Galit L. Dunietz, PhD, MPHThe assistant professor of neurology at the University of Michigan provided context on a previous study which suggested that treatment of obstructive sleep apnea may reduce the risk of subsequent dementia. [WATCH TIME: 3 minutes]
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Expanding the Understanding of ALS With New Methods: Brian Wainger, MD, PhDThe assistant professor of neurology and anesthesiology at Harvard Medical School discussed non-traditional ways ALS research is changing and where the focus should continue to be.
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Targeting Inflammation to Reduce Effects of Alzheimer Disease: RJ Tesi, MDThe president and chief executive officer of INmune Bio detailed the mechanistic advantages of XPro1595 as a potentially therapeutic benefit for patients with Alzheimer disease and dementia. [WATCH TIME: 5 minutes]
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Improving Recognition, Diagnosis of Psychogenic Nonepileptic Seizures: Becky Tilahun, PhDThe clinical psychologist at Cleveland Clinic provided insight on the tricky nature of diagnosing a patient with nonepileptic seizures and the difficult conversations that can ensue. [WATCH TIME: 3 minutes]
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The Quick Neurologic Examination Tool in the PICU: Apirada Thongsing, MDThe resident physician at Montefiore Medical Center shared her experience with the novel and standardized quick examination tool and the data presented at AAN 2022. [WATCH TIME: 3 minutes]
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Quality of Life Improvements in MS Following Wellness Program: Brian Hutchinson, PT, MSCSThe director of the Multiple Sclerosis Achievement Center in Sacramento discussed 3-year data from an assessment of the program, outlining key findings and future research efforts. [WATCH TIME: 6 minutes]
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WVE-004 Treatment for C9orf72 ALS and FTD: Merit Cudkowicz, MDThe director of the Sean M. Healey & AMG Center for ALS outlined the trial, which will evaluate ideal dose level and frequency of the investigational treatment for patients with C9-ALS and C9-FTD.
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Parkinson’s Disease: Advice for Community NeurologistsExpert neurologists provide insight on how to decide on an on-demand therapy for Parkinson’s disease and provide some general advice.
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Challenges of Targeting Cytokines in MS: Stephanie Blandford, MScThe PhD candidate at the neuroimmunology laboratory at Memorial University of Newfoundland discussed the potential of interleukin-1 receptor antagonist as a biomarker in MS disability as well as a therapeutic target.
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Addressing Unmet Needs in Narcolepsy Management: Practical Insight for Community-Based PhysiciansClosing out his discussion on narcolepsy management, Chris Winter, MD, highlights current unmet needs and shares practical advice for community physicians.
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James Grotta, MD: The Future of Stroke Care Going into 2021The vascular neurologist at Memorial Hermann Medical Group explained how clinical stroke care will change in 2021 amid the COVID-19 pandemic.
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Positive Signs From Prasinezumab in Parkinson Disease: Gennero Pagano, MD, MSc, PhDThe expert medical director at Roche provided detail on results from the phase 2 PASADENA study presented at the 2021 MDS Virtual Congress. [WATCH TIME: 3 minutes]
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The Ever-Expanding Multiple Sclerosis TherapeuticsJoin Ahmed Obeidat, MD, PhD; Mitchell Freedman, MD; and Suma Shah, MD, for the second program of this monthly series as they discuss the evolution of therapeutics for the treatment of multiple sclerosis.
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AUPN Leadership Minute Episode 26: Creating a Formal Junior Faculty Development PlanEpisode 9 of the AUPN Leadership Minute features Tracey A. Milligan, MD, of New York Medical College; and Larry B. Goldstein, MD, of University of Kentucky Medical Center. [WATCH TIME: 8 minutes]
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Integrating Machine Learning, Digital Platforms to Alzheimer Trials: David Bates, PhDThe chief executive officer and co-founder of Linus Health discussed screening tools for early cognitive decline and overcoming the complexities with using new-age technology. [WATCH TIME: 3 minutes]
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Future of Relapsing MS ManagementKey opinion leaders in multiple sclerosis (MS) discuss the future of relapsing MS management and unmet needs.
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Future Aspirations of Neonatal Seizure Research: Solomon Moshe, MD; Elissa Yozawitz, MDThe duo from Montefiore Medical Center discussed aspects of their recently published recommendations on neonatal seizure diagnosis that need further examining.
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Navigating an Expanding Treatment Toolbox for MS“Is more always better?”: The age-old question is more relevant than ever as clinicians and patients alike navigate an increasingly crowded MS treatment landscape.
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Optimizing the Migraine ConsultationProper diagnosis and effective treatment planning can drastically improve quality of life for individuals with migraine.
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Future of Treating Alzheimer DiseaseDrs Richard S. Isaacson and Marc E. Agronin look to the future of treating Alzheimer disease with the emphasis on early diagnosis.
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Assessing Efficacy of Fibroblast Cell Technology in MS and Directing Future Clinical Study: Hamid Khoja, PhDDiscussing data from an early safety study, the chief scientific officer of FibroBiologics commented on the benefits of a staggered approach to their clinical research in multiple sclerosis. [WATCH TIME: 5 minutes]
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AUPN Leadership Minute Episode 10: What Your CEO Wants From YouEpisode 10 of the AUPN Leadership Minute features Mud M Alvi, MD, of West Virginia University and Robert C. Byrd Health; and Albert L. Wright, Jr., the president and CEO of West Virginia University Health System. [WATCH TIME: 4 minutes]
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Next Steps in Understanding Cognitive Decline in Aging MS: Dejan Jakimovski, MD, PhDThe research assistant professor at the Buffalo Neuroimaging Analysis Center provided context on how different forms of multiple sclerosis impact cognitive decline in patients. [WATCH TIME: 4 minutes]
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Conducting Clinical Trials in Pediatric Migraine: Christina Szperka, MD, MSCEThe director of the Pediatric Headache Program at CHOP spoke on the challenges associated with clinical trials in pediatric migraine, further discussing the biggest advance made amid the COVID-19 pandemic. [WATCH TIME: 6 minutes]
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It Is Time to Redefine Outcomes in Pediatric Epilepsy SurgerySuccessful epilepsy surgery in adults has been followed by forced normalization, depression, and memory issues, resulting in questions about the use of the metrics in the study of broader outcomes—a problem even more prominent in pediatric epilepsy surgery.
