Authors
Latest:
Promising Nasal Administration Treatment for Non-Active Secondary Progressive MS: Tarun Singhal, MD, MBBSThe director of the PET Imaging Program in Neurologic Diseases at Brigham and Women’s Hospital talked about nasal administration of foralumab that shows promise in treating patients with non-active secondary progressive MS. [WATCH TIME: 5 minutes]
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Investigating Limb Swelling in Patients With Dravet Syndrome: Mandy Alhajj, DO, James Dolbow, DO & Neel Fotedar, MDA trio of experts from university hospitals discussed a study that aimed to uncover the prevalence and associations of limb swelling in patients with Dravet syndrome in hopes of improving care. [WATCH TIME: 5 minutes]
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Collecting Drug-Drug Interaction Data on Rimegepant: Elyse Stock, MDThe chief medical officer of Biohaven Pharmaceuticals discussed the findings of an assessment of rimegepant (Nurtec ODT) exposure with concomitant administration of inhibitors of P-gp and BCRP transporters.
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Advice for Advanced Practice Providers in Managing Sleep DisordersAdvanced practice practitioners share final pearls with their colleagues for the management of sleep disorders.
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Ongoing Research in MS Differentiation: Oliver Tobin, MBBCh, BAO, PhDThe associate professor of neurology at Mayo Clinic Rochester discusses technological advancements and research efforts in relation to differential multiple sclerosis.
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Nipocalimab Shows Promise as Myasthenia Gravis Treatment: Jeffrey Guptill, MD, MS, MHSThe associate professor of neurology and neurologist at Duke University discussed the positive results of nipocalimab, a monoclonal antibody, in patients with myasthenia gravis.
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Evolving Approaches to the Diagnosis and Management of Paraneoplastic Neurologic Syndromes: Ditte Primdahl, MD; Shailee Samir Shah, MDA duo of experts from Feinberg School of Medicine discussed the growing role of clinical algorithms, risk stratification, and treatment considerations in managing paraneoplastic neurologic syndromes alongside cancer therapies. [WATCH TIME: 4 minutes]
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Patient Evaluation for Excessive Daytime SleepinessExcessive daytime sleepiness is a hallmark of a number of sleep disorders, and ensuring the proper diagnosis and management of those presenting with it is crucial to care.
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Takeaways From Telehealth Use in Sleep Medicine: Lucas Donovan, MD, MSThe assistant professor in the division of pulmonary, critical care, and sleep medicine at the University of Washington discussed patients’ response to the use of telehealth when treating sleep disorders. [WATCH TIME: 2 minutes]
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Mechanistic Potential of Taldefgrobep Alfa in Spinal Muscular Atrophy: Lindsey Lee Lair, MDThe vice president of clinical development at Biohaven shed light on a newly initiated phase 3 study evaluating a promising agent for patients with all types of spinal muscular atrophy. [WATCH TIME: 2 minutes]
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R&D for NMOSD TherapiesDrs Mirla Avila, Mitzi Williams, Michael Levy, and Michael Yeaman comment on research and development priorities for clinical care and emerging therapies for NMOSD.
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Acute and Preventative Migraine Treatment: Advice for NeurologistsDr David Kudrow shares some advice for community neurologists on the acute and preventive treatment of migraine.
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Interdisciplinary Care Teams in Epilepsy Care: Lucretia Long, APRN-CNPThe associate clinical professor of neurology at OSU Wexner Medical Center discussed the state of interdisciplinary care for individuals with epilepsy, and how these care teams operate. [WATCH TIME: 2 minutes]
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Uncovering the Impact of Social Determinants on the Risk of Alzheimer Disease: Michael Yassa, PhDThe professor of neurology at the University of California, Irvine, talked about social determinants of health in Alzheimer disease and the importance of having diverse populations in clinical trials. [WATCH TIME: 4 minutes]
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Sex Dependent Decreases in REM Sleep After TBI and the Impact it May Have on RecoveryGrace Griesbach, PhD, the national director of clinical research for Centre for Neuro Skills, discussed the impact of REM sleep on memory following traumatic brain injury and the importance of considering sex as a biological variable.
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Early Clinical Use of Anti-Amyloid Therapy for Alzheimer Disease in Japan: Takeshi Iwatsubo, MD, PhDThe professor of neuropathology at the University of Tokyo School of Medicine talked about the latest data on lecanemab use in clinical practice for Alzheimer disease in Japan presented at CTAD 2024. [WATCH TIME: 4 minutes]
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VNTR Polymorphism and Treatment Selection in CIDPPanelists discuss how variable number tandem repeats (VNTR) 3/2 polymorphisms in the FCGRT gene may affect FcRn levels, immunoglobulin G (IgG) half-life, and the effectiveness of intravenous immunoglobulin (IVIg) therapy in chronic inflammatory demyelinating polyneuropathy (CIDP), highlighting early real-world evidence suggesting that genetic testing could help personalize treatment strategies to optimize outcomes for patients based on their specific genotypes.
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Flaws in Assessment Scales for Neuromuscular Conditions: Laurent Servais, MD, PhDThe professor of pediatric neuromuscular diseases at the University of Oxford provided commentary on the commonly used scales to assess neuromuscular function and where inconsistencies have been observed. [WATCH TIME: 7 minutes]
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Stephen L. Hauser, MD: Fenebrutinib and BTK Inhibition in Progressive MSThe director of the UCSF Weill Institute for Neuroscience spoke to the advantages of having agents that can be used across the spectrum of MS, and the role disease progression plays early on.
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Debunking Myths of Migraine’s Role in Dementia: Olivia Begasse de Dhaem, MD, FAHSThe headache specialist at Hartford Healthcare Headache Center emphasized the importance of avoiding unnecessary fear surrounding the potential link between migraine and dementia, as current evidence does not strongly support it being a significant risk factor. [WATCH TIME: 2 minutes]
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Immunization Strategy as a Potential Approach to Slowing Cognitive Decline in AD: Jean-Cosme Dodart, PhDThe senior vice president of research at Vaxxinity discussed recently published trial findings on a novel vaccine that targets Alzheimer disease and triggers the production of antibodies against toxic amyloid-ß peptides. [WATCH TIME: 9 minutes]
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Advancing ALS Through Gene Therapies, Early Intervention, and Multidisciplinary Care: Brian Lin, PhDThe research portfolio director at the Muscular Dystrophy Association discussed the evolving ALS therapeutic landscape, highlighting advances in genetic and RNA-based interventions. [WATCH TIME: 6 minutes]
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Ensuring Good Quality of Life With Good ON Time in Parkinson Disease: Khash Dashtipour, MD, PhDThe director of the Movement Disorders Division at Loma Linda University discussed the importance of understanding good ON time in Parkinson disease care, and how it can influence quality of life. [WATCH TIME: 5 minutes]
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AUPN Leadership Minute Episode 23: Time Savers for ChairsEpisode 23 of the AUPN Leadership Minute features Donald S. Higgins, Jr., MD, of the VHA and Albany Medical College; and Jun Li, MD, PhD, of Houston Methodist Hospital. [WATCH TIME: 3 minutes]
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Future Research on Subarachnoid Hemorrhage: Guilherme Dabus, MDThe codirector of interventional neuroradiology and vice-chief of the department of neuroscience at Baptist Health Miami Neuroscience Institute discussed the questions that still remain with identifying and treating subarachnoid hemorrhage. [WATCH TIME: 3 minutes]
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Machine Learning Techniques for Predicting Stroke Risk in Adults: Michael Pencina, PhDThe vice dean for data science at Duke University School of Medicine spoke about the major disparities observed in models that assess stroke risk. [WATCH TIME: 4 minutes]
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Clinical Program and Next Steps for Zorevunersen as Potential Disease-Modifying Treatment for Dravet: Barry Ticho, MD, PhDThe chief medical officer at Stoke Therapeutics discussed recent developments for zorevunersen, including the significance of breakthrough therapy designation and its plan for a phase 3 trial. [WATCH TIME: 5 minutes]
Latest:
Navigating the Transition From Pediatric to Adult MS Care: Yolanda Wheeler, PhD, CPNP-AC, MSCNThe assistant professor at the University of Alabama at Birmingham discussed the transition from pediatric to adult care for patients with multiple sclerosis as well as the challenges presented in diagnosis, treatment, and understanding the long-term impact of the disease. [WATCH TIME: 5 minutes]
Latest:
Final Advice for Clinicians Treating NarcolepsyDrs Thorpy, Dogan, Doghramji, and Kushida share clinical pearls for primary care providers who are taking care of patients with narcolepsy.
