"Mind Moments," a podcast from NeurologyLive, brings you an exclusive look into the FDA approval of aducanumab (Aduhelm; Biogen) for the treatment of Alzheimer disease.
The Mind Moments podcast features exclusive interviews with leaders in the field discussing the latest research and disease management strategies across the breadth of neurology, including epilepsy, multiple sclerosis, Parkinson disease, dementia, sleep disorders, and more.
Episode 39, "A Controversial FDA Decision," features insights from a number of individuals in the Alzheimer disease space, including neurologists, psychiatrists, and advocacy partners who share their varying and nuanced opinions on this decision to better understand not only what this approval means for clinical care, but what the downstream effects of it may be. Those individuals, in order of appearance, are:
2:50 – Sabbagh's reaction to the FDA approval
4:50 – Porsteinsson on the impact on amyloid identification
7:55 – Knopman on the accelerated approval pathway
9:20 – Schneider on the FDA label for aducanumab
12:35 – Howard and Knopman on the utility of phase 4 data
14:20 – Porsteinsson on the potential of a multipronged approach
16:40 – Howard on the challenge of a multipronged approach
18:45 – Knopman on the impact on clinical development
21:35 – Kremer on access to aducanumab
24:25 – Scharre on the remaining need to identify patients earlier
27:55 – Kremer on what's still left to accomplish in Alzheimer
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