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Episode 49: Altering the View of MS With a Topographical Model

"Mind Moments," a podcast from NeurologyLive, brings you an exclusive interview with Stephen Krieger, MD.

Episode 49 of the NeurologyLive Mind Moments podcast is now live! Scroll down to listen or click here to subscribe on your favorite streaming service.

The Mind Moments podcast features exclusive interviews with leaders in the field discussing the latest research and disease management strategies across the breadth of neurology, including epilepsy, multiple sclerosis (MS), Parkinson disease, dementia, sleep disorders, and more.

Episode 49, "Altering the View of MS With a Topographical Model" features an exclusive interview with Stephen Krieger, MD, professor of neurology, Icahn School of Medicine, and staff neurologist, Corinne Goldsmith Dickinson Center for MS, Mount Sinai. Krieger discussed the development of his topographical model of MS and how it has been leveraged to this point, as well as offered insight into a recently initiated effort with it that he presented at the 37th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), October 13-15, 2021.

More information, including the iPad app that is available, can be found here.

The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here:


1:15 – Background on the topographical model and its development

6:00 – Current utilization of the model and its insight into the MS disease course thus far

11:10 – The potential for the model to impact clinical care

13:05 – Neurology News Minute

15:15 – Topographical model-informed data in early MS and ECTRIMS presentation recap

21:10 – The need for better and improved tools to measure disease progression

25:00 – The future use of the topographical model of MS and closing thoughts

Click here to subscribe to the Mind Moments podcast. Be sure to leave a rating and review for the show. Thanks for listening!

1. Krieger SC, Cook K, De Nino S, Fletcher M. The topographical model of multiple sclerosis: A dynamic visualization of disease course. Neurol Neuroimmunol Neuroinflamm. 2016;3. doi:10.1212/NXI.0000000000000279
2. Laitman BM, Cook K, Fletcher M, Krieger SC. The topographical model of MS: Empirical evaluation of the recapitulation hypothesis. Mult Scler J Exper Transl Clin. 2018;4(4). doi:10.1177/2055217318806527