Our Nov. news & research list includes 2 successful genetic Alzheimer treatments in mouse models and a potential drug for Parkinson disease psychosis.
We present a selection of interesting neurology articles for the month of November in the following slides. See the slide legends for links to the article summaries.
Interesting Neuro: Alzheimer Studies & Stroke Drug. November 2015
Performance of Glial Fibrillary Acidic Protein in Detecting Traumatic Intracranial Lesions on Computed Tomography in Children and Youth with Mild Head Trauma. Abstract link.*** Loss of Consciousness at Onset of Subarachnoid Hemorrhage as an Important Marker of Early Brain Injury. Abstract link.
The Incidence of Benzodiazepine and Related Drug Use in Persons with and without Alzheimer’s Disease. Abstract link. **** Olfactory Deficits Predict Response to Cholinesterase Inhibitors in MCI Due to Alzheimer. Abstract link. 8th Clinical Trials Conference on Alzheimer's Disease (CTAD). Nov. 6, 2015. Poster P2-46.
Alzheimer’s Disease-Causing Proline Substitutions Lead to Presenilin 1 Aggregation and Malfunction. Abstract link. *** Raloxifene for Women with Alzheimer Disease. Abstract link.
Arginase 1+ Microglia Reduce Aβ Plaque Deposition during IL-1β-Dependent Neuroinflammation. Abstract link.*** Viral Gene Transfer of APPsα Rescues Synaptic Failure in an Alzheimer’s Disease Mouse Model. Abstract link.
A Retrospective Cross-Sectional Study of the Prevalence of Generalized Convulsive Status Epilepticus in Traumatic Brain Injury: United States 2002â2010. Abstract link.**** Hospital-Diagnosed Pertussis Infection in Children and Long-term Risk of Epilepsy. Abstract link.
Optical Coherence Tomography Reflects Brain Atrophy in Multiple Sclerosis: A Four-Year Study. Abstract link. ****Association of Vitamin D Levels with Multiple Sclerosis Activity and Progression in Patients Receiving Interferon Beta-1b. Abstract link.
Color Discrimination in Patients with Gaucher Disease and Parkinson Disease. Abstract link.****ACADIA Pharmaceuticals Announces FDA Priority Review of NUPLAZID⢠(Pimavanserin). Press Release.
The Effects of Socioeconomic Status on Stroke Risk and Outcomes. Abstract link. ****Therapeutic Potential of Tenecteplase in the Management of Acute Ischemic Stroke. Abstract link.