|Poll|December 17, 2014

Lhermitte-Duclose Disease: Test Your IQ

Test your knowledge about this hamartomatous tumor of the cerebellar cortex.

A 39-year-old woman presented with 2-month history of progressively worsening headache and right-sided ataxia. Brain MRI showed a nonenhancing, T1 hypointense mass on the right cerebellar hemisphere, consistent with Lhermitte-Duclos disease

Which of the following statements about Lhermitte-Duclose disease is false?

A. LDD is also known as dysplastic gangliocytoma of the cerebellum.
B. It is a rare, slow-growing, benign lesion of the cerebellum.
C. It arises in the cerebellar hemispheres and extends into the vermis.
D. It is often asymptomatic in early life but usually becomes apparent in the third and fourth decades.
E. The most frequent complaints are headaches and ataxia.
F. About one-third of patients have associated cranial nerve palsies and long tract dysfunction.
G. It has been linked to Cowden syndrome

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