Quiz|Articles|October 18, 2026 (Updated: September 23, 2026)

NeurologyLive® Brain Games: October 18, 2026

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Key Takeaways

  • Weekly publication cadence is Sunday morning, with content written by physicians, clinicians, and neurological care and advocacy experts.
  • Questions span major neurology domains, including dementia/Alzheimer disease, epilepsy, headache, movement disorders, multiple sclerosis, neuromuscular and sleep disorders, and stroke.
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Test your neurology knowledge with NeurologyLive®'s weekly quiz series, featuring questions on a variety of clinical and historical neurology topics. This week's topic is biomarkers in multiple sclerosis!

Welcome to NeurologyLive® Brain Games! This weekly quiz series, which goes live every Sunday morning, will feature questions on a variety of clinical and historical neurology topics, written by physicians, clinicians, and experts in the fields of neurological care and advocacy.

Test your mettle each week with 3 questions that cover a variety of aspects in the field of neurology, with a focus on dementia and Alzheimer disease, epilepsy and seizure disorders, headache and migraine, movement disorders, multiple sclerosis, neuromuscular disorders, sleep disorders, and stroke and cerebrovascular disease.

This week's questions includes the theme of biomarkers in multiple sclerosis!

Click here to check out the prior iterations of Brain Games.

Interested in submitting quiz questions? Contact our editor, Marco Meglio, via email: mmeglio@neurologylive.com.

A 34-year-old patient with relapsing-remitting multiple sclerosis (RRMS) is clinically stable on a disease-modifying therapy. Routine MRI shows no new lesions, but serum neurofilament light chain (sNfL) has increased substantially from the patient's prior baseline. Which interpretation is most appropriate?


A clinician is considering serum glial fibrillary acidic protein (sGFAP) and sNfL to help characterize disease activity in a patient with progressive MS. Which statement best describes the biological distinction between these biomarkers?


A patient undergoing evaluation for possible MS has a lumbar puncture. The cerebrospinal fluid (CSF) demonstrates evidence of intrathecal immunoglobulin synthesis. Which finding is most directly used to demonstrate this process in routine MS diagnostic workups?


How did you do on this week's quiz? Let us know with a response to the poll below. Don't forget to share and compare your results with your friends!

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