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Opinion|Videos|August 28, 2024

Treatments With Higher Efficacy and Relapses in NMOSD

Author(s)Michael Levy, MD, PhD

This discussion examines how disability accumulation may be influenced by the use of less efficacious treatments, compares the efficacy of novel and traditional NMOSD agents in clinical practice, and reviews relapse rates associated with FDA-approved treatments versus off-label and older therapies.

Episodes in this series

EP. 1 Relapses and Disability Accumulation in NMOSD

EP. 1 Relapses and Disability Accumulation in NMOSD

EP. 2 Treatments With Higher Efficacy and Relapses in NMOSD

EP. 2 Treatments With Higher Efficacy and Relapses in NMOSD

EP. 3 Ravulizumab Long-Term Data and Management of NMOSD

EP. 3 Ravulizumab Long-Term Data and Management of NMOSD

EP. 4 The Evolving Understanding of NMOSD Pathophysiology and the Role of Complement System

EP. 4 The Evolving Understanding of NMOSD Pathophysiology and the Role of Complement System

EP. 5 Treatment Options to Manage and Prevent Relapses in NMOSD

EP. 5 Treatment Options to Manage and Prevent Relapses in NMOSD

EP. 6 Importance of Diverse Mechanisms of Action to Effectively Treat NMOSD

EP. 6 Importance of Diverse Mechanisms of Action to Effectively Treat NMOSD

EP. 7 Complement Inhibitors in NMOSD

EP. 7 Complement Inhibitors in NMOSD

EP. 8 Meningococcal Infection and NMOSD

EP. 8 Meningococcal Infection and NMOSD

EP. 9 Long-term NMOSD Data

EP. 9 Long-term NMOSD Data

EP. 10 Use of Long-term NMOSD Data in Clinical Practice

EP. 10 Use of Long-term NMOSD Data in Clinical Practice

Video content above is prompted by the following:

To what extent can disability accumulation be attributed to the use of less efficacious treatments?
Discuss the use of more efficacious (and novel) and less efficacious (and traditional) neuromyelitis optica spectrum disorder agents in clinical practice.
What do we know about relapse rates with FDA-approved treatments (eculizumab, satralizumab, inebilizumab, ravulizumab) and off label and older treatments (azathioprine, mycophenolate, and rituximab)?

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