Use and Uptake of Newer Narcolepsy Treatments in Clinical Practice

EP: 1.Classic Features of Narcolepsy

EP: 2.The Frequency of Occurrence of Narcolepsy Symptoms

EP: 3.Contributing Factors to Narcolepsy

EP: 4.Quality of Life of Patients With Narcolepsy

EP: 5.Treatment Selection in Patients With Narcolepsy

EP: 6.Treatment Classes for Narcolepsy

EP: 7.Safety Data on Emerging Treatment of Narcolepsy

EP: 8.Use of Narcolepsy Treatments in Different Patients: Part 1

EP: 9.Use of Narcolepsy Treatments in Different Patients: Part 2

EP: 10.Treating Narcolepsy in Pregnancy

EP: 11.Abuse and Dependency Potential With Newer Narcolepsy Treatment

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EP: 12.Use and Uptake of Newer Narcolepsy Treatments in Clinical Practice

EP: 13.Criteria for Changing Treatment in Narcolepsy: Part 1

EP: 14.Criteria for Changing Treatment in Narcolepsy: Part 2

EP: 15.Drug Holidays in Narcolepsy

EP: 16.Ongoing Studies and New Treatments for Narcolepsy

EP: 17.Final Advice for Clinicians Treating Narcolepsy

This is a video synopsis/summary of a panel discussion involving Michael Thorpy, MD; Karl Doghramji, MD, FAASM, DFAPA; Clete Kushida, MD, PhD; and Richard K Bogan, MD.

Experts discusses the long-term safety and effectiveness of various medications used for narcolepsy treatment. Studies, lasting up to 12 months, have shown that medications like pitolisant, solriamfetol, and sodium oxybate are safe and effective over extended periods. Additionally, open-label extension studies have confirmed the continued safety and efficacy of these medications beyond the initial study periods.

The conversation then shifts to the impact of newer medications on narcolepsy treatment. Polypharmacy, the use of multiple medications, is common due to concerns about tolerance, rebound, and withdrawal, particularly with schedule 2 drugs. The approach to treatment involves tailoring medication regimens to individual patient needs, considering factors such as comorbidities, mood, and response to treatment. Polypharmacy is seen as an important aspect of managing narcolepsy effectively, with adjustments made based on ongoing assessment of symptoms and quality of life. Overall, treatment is viewed as a continuum rather than a 1-time prescription, emphasizing the need for personalized and flexible approaches.

Video synopsis is AI-generated and reviewed by NeurologyLive editorial staff.