Parkinson Gene Therapy Targets Growth Factors
Scientists are testing alternative therapeutic approaches that may delay disease progression and even protect and regenerate neurons.
Alzheimer Risk May Rise With Common Meds
Anticholinergics could confer an increased risk, one dependent on the dose and amount of use. Give them to older patients or consider alternatives?
Sleep Protein Curbs Neuron Death in Parkinson
Orexin B protects vulnerable midbrain neurons from degeneration and preserves their function. This sleep-promoting protein could provide a new target for potential treatments.
Immunosuppression, Stem Cells Halt MS
HDIT/HCT could induce sustained remission and neurological improvements in patients with multiple sclerosis.
Block Microglial Benefits in Alzheimer
Prostaglandin may block protective microglial cells in Alzheimer disease, a study shows. This work could form the basis for future therapies.
MRI May ID Hard-to-tell-apart Brain Diseases
Parkinson and other neurodegenerative diseases are hard to distinguish. Surface-based MRI shows promise as a diagnostic tool.
Brain Aging, Development, and Disease Explained
Identification of a brain circuit implicated in Alzheimer disease and schizophrenia could aid in comprehension of brain disorders and point to prevention strategies.
For Tension Headache, Combo Rx Tops Acetaminophen
Pain relief is better with a triple combination medication that includes acetaminophen than with acetaminophen by itself, researchers found, suggesting a new therapeutic option.
MRI May Advance Parkinson Gene Therapy
Up until now, these treatments have not produced promising efficacy results in clinical trials. MRI could show the way.
What MS Therapies Patients Want
As more treatments become available, patients will have more preferences and will play a more prominent role in directing choices.
MRI Predicts MS Risk, Even Without Symptoms
Determining who is at risk for MS remains difficult, and symptoms may take time to develop even in patients who already have some destroyed myelin. MRI may help.
HSV Linked to Alzheimer Disease
Could the common herpes simplex virus be associated with Alzheimer disease? These researchers think it is possible.
Multiple Sclerosis Rx: IGF-1?
A new study provides hope for MS treatment with IGF-1, which could ultimately halt the attack of T effector cells on myelin, thereby stopping disease progression.
Orexin and Alzheimer: A Link to Impaired Sleep
Increased orexin in this disorder is associated with disease severity, total tau protein levels, sleep impairment, and cognitive deterioration.
Use a Saliva Test to ID Neurodegenerative Disease?
Why ask patients to “spit in a cup”? Statistically significant protein differences have been found in Alzheimer disease saliva, and trends have been observed for Parkinson disease.
For Patients With Parkinson: It Takes Two to Tango
Tango may be not only a vibrant dance of passion but also a therapeutic one. Symptoms and socialization may be improved.
Are Alzheimer Biomarkers Clinically Relevant?
Cerebrospinal fluid biomarker assessment could conceivably become a part of routine clinical practice.
Memantine and Recovery After Stroke
The Alzheimer drug may help repair some damage caused by stroke. In a rodent model, treated animals showed improved motor behavior and restored sensory mapping in the cortex. Here, more about the proposed mechanism.
Coffee: Drink Java for Good Neurologic Health?
The remarkable coffee bean is associated with reduced prevalence of several diseases, including Parkinson disease, Alzheimer disease, cancer, cardiovascular disease, and diabetes.
Nutrition: What Role in Preventing or Delaying Progression of Parkinson Disease?
This study indicates that your mother was right about eating your fruits and vegetables: results suggest that eating some foods and avoiding others could be a nutrient prescription for Parkinson disease.
CSF Biomarkers and Alzheimer Disease: Ready for the Clinic?
Here: an update on the current state of CSF fluid-borne markers for Alzheimer disease and what they may portend.