Authors
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The Growing Epidemic of TBI in Older PatientsDespite advances in neurology, a silent epidemic of older adults who sustain a TBI is growing. The authors provide tools and tips for a geriatric approach to treatment.
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Complementary and Alternative Therapies for TBI: Key Points for CliniciansThe CAM options described here may help prevent trauma-related neurodegeneration over the long term.
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Effective Treatment of Essential Palatal Tremor and Coexistent Bipolar Disorder: A Case ReportClicking sounds in the patient’s ears were initially thought to be auditory hallucinations, but a thorough neurological examination revealed the true cause.
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Epilepsy Surgery, Part 1: Refractory Seizures and Presurgical EvaluationAt least 30% of patients with epilepsy have seizures that are incompletely controlled by medical therapy; thus, nonpharmacological options are important for comprehensive care.
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AAN Guidelines on Use of fMRI for Presurgical Mapping in EpilepsyPatients with drug-resistant seizures should have an epilepsy center evaluation to confirm the diagnosis and determine the epilepsy syndrome and possible candidacy for neurosurgery. Guidelines here.
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A History of Migraine: Gender RatioAround three times more women than men have migraine. This marked difference in prevalence is one of the most well-known features of the illness. Here's what history tells us.
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Benefits of Martial Arts on Movement DisordersThis podcast discusses preliminary evidence about the effects of karate on quality of life and several measures of gait, balance, and mobility in patients with PD.
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Music Therapy Unites the Arts and Medicine to Help PatientsTwo medical students who are conservatory-trained musicians describe a memorable performance at a center for older adults with dementia.
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Music Therapy Unites the Arts and Medicine to Help PatientsTwo medical students who are conservatory-trained musicians describe a memorable performance at a center for older adults with dementia.
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Phase 2 Trial for Angelman Syndrome UnderwayIn this podcast, Heidi Moawad, MD interviews Cesar Ochoa-Lubinoff, MD, MPH, FAAP, about recent encouraging clinical trial results in patients with Angelman syndrome.
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Genetic Testing for Huntington DiseaseThe profound consequences of the results guide decisions about testing. Who should be tested? And, just as important, who should not?
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Connecting With Neurology Patients Through MusicAn interview with a neurologist who found that merely writing medical articles cannot express the impact an illness can have on patients, both literally and emotionally.
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Developing Targeted Therapeutics in Angelman SyndromeThe genomic revolution has led to increasing opportunities to address complex neurodevelopmental conditions, taking a genetics-first approach.
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New Treatment for Rare Autoimmune DiseaseA new treatment for NMOSD has been found to reduce relapse, decrease re-hospitalizations, and hinder the need to treat acute attacks with corticosteroids and plasma exchange.
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Prion-like Molecular Mechanisms in Alzheimer DiseaseAlthough Alzheimer disease is not infectious by any common definition of the term, research over the past 20 years has confirmed long-standing speculation that the molecular mechanism driving neurodegeneration is fundamentally the same in Alzheimer disease and the prototypical infectious proteopathy-prion disease.
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A Time to Recognize and Enhance Understanding of Migraine Disorders: Jessica Ailani, MDThe director of the MedStar Georgetown Headache Center talked about recognizing the struggles of patients with migraine disorders and the importance of bringing awareness of available treatments to this patient population. [WATCH TIME: 5 minutes]
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FibroGen's Duchenne Muscular Dystrophy Antibody Pamrevlumab Falls Short in Phase 3The study did not meet its primary end point of change from baseline in Performance of the Upper Limb 2.0 score at 1 year.
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FDA Rejects Duchenne Muscular Dystrophy Drug Golodirsen, Citing Safety ConcernsThe regulatory agency cited 2 concerns in the complete response letter: the risk of infections related to intravenous infusion ports and renal toxicity.
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Unusual New Onset Seizures in a Healthy, Young Adult MaleA 23-year-old male college student presents with first generalized tonic-clonic seizure followed by episodes of violent psychosis.
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Tolebrutinib Slows Disability Worsening in GEMINI Trials of Relapsing MS, Despite Failing to Meet Primary End PointThe positive finding on the secondary end point of 6-month confirmed disability worsening supports the data from the phase 3 HERCULES trial in secondary progressive multiple sclerosis.
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Using the Ketogenic Diet to Treat Intractable Epilepsy in Case of Glycine EncephalopathyA boy diagnosed with glycine encephalopathy in the newborn period was initiated on the ketogenic diet at 11 years-old for the treatment of medication refractory epilepsy.
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Understanding Cerebral Venous Thrombosis: Rare But Sometimes FatalThe prognosis of cerebral venous thrombosis (CVT) is favorable compared with other types of stroke: almost 80% of patients with CVT recover without functional disability. Nevertheless, 5% to 10% of patients die in the acute phase.
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Understanding Cerebral Venous Thrombosis: Rare But Sometimes FatalThe prognosis of cerebral venous thrombosis (CVT) is favorable compared with other types of stroke: almost 80% of patients with CVT recover without functional disability. Nevertheless, 5% to 10% of patients die in the acute phase.
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Understanding Cerebral Venous Thrombosis: Rare But Sometimes FatalThe prognosis of cerebral venous thrombosis (CVT) is favorable compared with other types of stroke: almost 80% of patients with CVT recover without functional disability. Nevertheless, 5% to 10% of patients die in the acute phase.
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Case Report: New Onset Paroxysmal Episodes in an InfantA newborn presents with new onset episodes of lateral gaze deviation with extremity stiffening.
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Closing the Treatment Gap in Progressive MSNew biomarkers of disease activity may help better vet investigational therapies aimed at slowing the insidious neurodegeneration seen in primary progressive multiple sclerosis.
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Exploring the Impact of Circadian Rhythms on Glial Function and Alzheimer DiseaseErik Musiek, MD, PhD, a professor of neurology at Washington University in St. Louis, provided clinical insight on a presentation from ANA 2024 highlighting the intricate relationship between circadian rhythms, glial activation, and neuroinflammation in Alzheimer disease.
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Cyclic Vomiting, Incontinence in a Young BoyAn 8 year old boy with genetically confirmed neurofibromatosis type 1 presents with first generalized seizure.
