Disease Overview of CDKL5 Deficiency Disorder

Raj Rajaraman, MD, MS, discussed early clinical indicators of CDKL5 deficiency disorder and emphasized the importance of timely, comprehensive genetic testing strategies.

Raj Rajaraman, MD, MS, discussed the clinical and genetic distinctions of CDKL5 deficiency disorder, emphasizing its early onset, unique seizure patterns, and differentiation from related syndromes.

Raj Rajaraman, MD, MS, discussed the comprehensive, team-based approach to managing CDD, highlighting the complex interplay of seizures, developmental delays, cortical visual impairment, gastrointestinal issues, and orthopedic concerns.

Raj Rajaraman, MD, MS, emphasized that CDKL5 diagnosis relies on early genetic testing rather than EEG findings, given the absence of a consistent electrographic signature.

Raj Rajaraman, MD, MS, discussed the broad treatment landscape for CDD, highlighting current therapies, neuromodulation, surgical options, and emerging gene-targeted strategies.

Raj Rajaraman, MD, MS, discussed the variable seizure patterns, treatment challenges, and EEG monitoring considerations in patients with CDKL5 deficiency disorder.