DORA Class for Treating Insomnia
July 4th 2025A panelist discusses how dual orexin receptor antagonists (DORAs) offer a novel approach to treating insomnia by reducing wakefulness rather than inducing sedation, highlighting the importance of patient education on their gradual onset, distinct mechanism, and the need for consistent use to achieve long-term benefits.
Revisiting Deep Brain Stimulation in a Pediatric-Onset Dystonia Case: Pamela Zeilman, NP
July 3rd 2025The nurse practitioner in the Center for Movement Disorders & Neurorestoration at the University of Florida discussed a complex case of childhood-onset dystonia treated with DBS. [WATCH TIME: 6 minutes]
Overviewing Pivotal Phase 3 TEMPLE Trial of Atogepant vs Topiramate: Jessica Ailani, MD
July 3rd 2025The director of the MedStar Georgetown Headache Center discussed results from the phase 3 TEMPLE trial, which showed improved tolerability and cognitive outcomes with atogepant vs topiramate in episodic migraine. [WATCH TIME: 5 minutes]
Validating a Wearable-Based Classifier to Detect iRBD: Emmanuel During, MD
July 2nd 2025The associate professor of neurology at the Icahn School of Medicine at Mount Sinai explained how his team validated an iRBD actigraphy classifier across new devices and datasets to enhance early, scalable screening for neurodegenerative disease. [WATCH TIME: 5 minutes]
The Future of Duchenne Muscular Dystrophy Treatment: Expert Insights on Gene Therapy
July 2nd 2025A panelist discusses how ongoing research into next-generation DMD therapies aims to improve delivery methods, develop better vectors that can carry larger dystrophin genes, and determine optimal treatment timing, with evidence suggesting earlier intervention may be more effective.
Understanding the Phenomenology and Impact of Psychosis in Parkinson Disease: William Ondo, MD
June 30th 2025The director of the Movement Disorders Clinic at Houston Methodist Hospital discussed the distinct features, progression, and clinical implications of psychosis in Parkinson disease. [WATCH TIME: 4 minutes]
Incorporating Palliative Care Principles into Movement Disorder Management: Jennifer Corcoran, MD
June 30th 2025The movement disorder neurologist at University of Rochester Medical Center outlined a 5-pillar model that emphasized holistic care, patient-centered communication, and proactive support in movement disorders. [WATCH TIME: 5 minutes]
Improving the Management of Parkinson Through Psychological Interventions: Marcia Pasqualini, PhD
June 30th 2025The professor of psychology at Avila University discussed how cognitive behavioral therapy and social support can help to improve quality of life for individuals with Parkinson disease. [WATCH TIME: 4 minutes]
Common Challenges in Chronic Insomnia Management
June 27th 2025A panelist discusses how managing chronic insomnia requires setting realistic patient expectations around gradual improvement, emphasizing consistent effort over time, and using both clinical tools and patient feedback to assess progress toward more restorative sleep.
Patient and Clinician Perspectives on Empathy in Parkinson Disease Care: Daniel Irizarry, MD
June 27th 2025The medical advisor at Tactical Medical Solutions shared insights from both clinical and personal perspectives on the importance of empathy and active listening in managing Parkinson disease. [WATCH TIME: 3 minutes]
Balancing MS Relapse Risk With Personalized Therapy Decisions: Gabrielle Macaron, MD
June 26th 2025The assistant professor in the Department of Neuroscience at Université de Montréal discussed the importance of weighing the risks of multiple sclerosis against treatment risks, emphasizing individualized care. [WATCH TIME: 4 minutes]
Considering New Duchenne Muscular Dystrophy Therapies: Excon Skipping and Gene Therapy
June 25th 2025A panelist discusses how older DMD patients might benefit from newer genetic therapies including gene therapy and exon skipping, though eligibility depends on specific mutations and absence of pre-existing immunity to AAV vectors.
Case 2 Overview: Patient at 16 with Duchenne Muscular Dystrophy
June 25th 2025A panelist discusses how a 16-year-old DMD patient shows more rapid disease progression despite early steroid treatment, with early onset cardiac issues, scoliosis, and increasing upper limb weakness requiring comprehensive specialist care.
Understanding ALKS 2680’s Wake-Promoting Effects Through qEEG: Julia Chapman, PhD
June 24th 2025The postdoctoral researcher at the Woolcock Institute of Medical Research highlighted EEG-based evidence supporting ALKS 2680's wake-promoting effects in patients with narcolepsy and idiopathic hypersomnia. [WATCH TIME: 3 minutes]
Patients Voicing Key Needs for Migraine Care and Advocacy: Elizabeth W. Leroux, MD, FRCPC
June 24th 2025The neurologist and headache specialist at the Montreal Neurological Clinic spoke about a recent national survey presented at AHS 2025 that revealed insightful patient perspectives in migraine. [WATCH TIME: 5 minutes]
What Newly Approved STS101 Brings to Migraine Treatment Landscape: Stewart Tepper, MD
June 23rd 2025The professor of neurology at the Geisel School of Medicine at Dartmouth broke down the FDA approval of STS101, a new DHE nasal powder, and its implications for acute migraine care. [WATCH TIME: 7 minutes]
Clinicians Express Growing Optimism in ALS Research and Treatment Advancements
June 23rd 2025Experts in ALS care and research shared their optimism about emerging treatments, aiming to deepen scientific understanding, and the potential role of advocacy in accelerating progress. [WATCH TIME: 4 minutes]
Chronic Insomnia Diagnosis and Management
June 20th 2025A panelist discusses how managing chronic insomnia requires a comprehensive, multifaceted approach that integrates behavioral interventions like CBT-I with pharmacologic treatments, guided by thorough sleep assessments and tailored to each patient’s specific sleep patterns and comorbid conditions.