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NeurologyLive® Top Expert Interviews: November 2021

Expert clinicians offer their perspectives on transitional care in pediatric MS, a biomarker for SUDEP, and a novel approach to narcolepsy, among other topics.

The NeurologyLive® team has been as busy as always bringing you the latest clinical news and research updates in neurology over the last month, including conducting several interviews with experts across a number of different and varying topics.

Among these included a conversation on the use of focused ultrasound to open the blood-brain barrier for Alzheimer disease therapy with Ali Rezai, MD; the potential of MCHR1 antagonists in the treatment of narcolepsy with Thomas Scammell, MD; preparing teens with multiple sclerosis for the transition to adult care with Vikram Bhise, MD; the findings of the NAVIGATE-ESUS trial in stroke with Alexander Merkler, MD, MS; and the possibility of short-term heart rate variability as a biomarker for sudden unexplained death in epilepsy with Orrin Devinsky, MD.

Click through the slides to see and read more from each expert’s exclusive conversation with NeurologyLive® in November 2021.

To hear more insight from experts in the clinical care of patients and leading researchers in neurology, check out more of NeurologyLive®'s videos.

REFERENCES
1. Harmony Biosciences acquires asset with novel mechanism of action for the potential treatment of narcolepsy and other are neurological diseases. News release. Harmony Biosciences. August 9, 2021. Accessed November 1, 2021. https://www.prnewswire.com/news-releases/harmony-biosciences-acquires-asset-with-novel-mechanism-of-action-for-the-potential-treatment-of-narcolepsy-and-other-rare-neurological-diseases-301350524.html
2. Naganuma F, Bandaru SS, Absi G, Mahoney CE, Scammell TE, Vetrivelan R. Melanin-concentrating hormone neurons contribute to dysregulation of rapid eye movement sleep in narcolepsy. Neurobiol Dis. 2018;120:11-24. doi:10.1016/j.nbd.2018.08.012
3. Veras JM, Thoby E, Nallapati S, Jimenez M, Bhise V. No one really plans to have multiple sclerosis: Transition readiness and quality of life in pediatric multiple sclerosis. Presented at: 2021 CMSC Annual Meeting; October 25-28. Abstract PSY06.
4. Merkler AE, Pearce LA, Kasner SE, et al. Left ventricular dysfunction among patients with embolic stroke of undetermined source and the effect of rivaroxaban vs aspirin: a subgroup analysis of the NAVIGATE ESUS randomized clinical trial. JAMA Neurol. Published online October 25, 2021. doi:10.1001/jamaneurol.2021.3828
5. Sivathamboo S, Friedman D, Laze J, et al. Association of short-term heart rate variability and sudden unexpected death in epilepsy. Neurology. Published online October 14, 2021. doi:10.1212/WNL.0000000000012946