Switching Therapies for Patients with Multiple Sclerosis
Stephen Krieger, MD; Daniel Bandari, MD, MS; Bruce Hughes, MD; Mitzi Williams, MD; and Heidi Crayton, MD, discuss their approach to switching treatments for patients with multiple sclerosis and the timing between therapies.
Stephen Krieger, MD: How about changing a patient’s medicine? The difference between changing a patient’s medicine because of efficacy concerns, as you said, treating to target and trying to not let anything happen vs changing medicines because of safety concerns. I feel like we emphasize a lot the switching because of efficacy failure, but maybe we need to talk a little about switching for safety or for comorbidities. Can you talk about how you do that, switch between classes for safety reasons, trying to maximize treating the disease, but being mindful of the safety issues?