Understanding Frequency, Age, and Sex Associations With Autoimmune Encephalitis Biomarkers: Amy Kunchok, MD
The staff neurologist at Cleveland Clinic’s Mellen Center for Multiple Sclerosis Treatment and Research discussed the results of a new study on age and sex as determinants of autoimmune encephalitis. [WATCH TIME: 3 minutes]
WATCH TIME: 3 minutes
"So far, most of the studies of autoimmune encephalitis have come from single centers. They are often small, descriptive cohorts that give us clinical information, which has paved a lot of the understanding so far. In this study, we tried to take a big picture or big data perspective."
Although uncommon, autoimmune/paraneoplastic encephalitis/encephalopathy (AE) has become an increasingly recognized cognition with the use of antibody biomarkers. Due to its rarity, it has been hard for clinicians to gather large-scale data, making it one of the more difficult conditions to research. Although, a new study led by Amy Kunchok, MD, the largest of its kind to date, included 42032 patients who were tested for AE antibody biomarkers (AE-Abs) in serum and/or cerebrospinal fluid (CSF).
The results, presented at the
Kunchok, staff neurologist, Mellen Center for Multiple Sclerosis Treatment and Research,
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REFERENCE
1. Kunchok, A, McKeon A, Zekeridou A, et al. Autoimmune encephalitis antibody biomarkers: frequency, age and sex associations. Presented at: ACTRIMS Forum 2022; February 24-26; West Palm Beach, Florida. Abstract CE2.4
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