Marco Meglio, Editor for NeurologyLive, has been with the team since October 2019. Follow him on Twitter @marcomeglio1 or email him at mmeglio@neurologylive.com
NeuroVoices: Jessica Ailani, MD, on Emerging Research in Migraine, CGRPs, and PACAP Pathway
October 11th 2023The director of the MedStar Georgetown Headache Center gave commentary on the advances in the treatment of migraine, ways to better utilize CGRP medications, and the introduction of PACAP-targeting agents and their relevancy.
FDA Issues Complete Response Letter to Alnylam for Patisiran in ATTR Amyloidosis Cardiomyopathy
October 9th 2023In a phase 3 study, patisiran met its primary and first secondary end point, demonstrating significant benefit in functional capacity, quality of life, and health status, in comparison with placebo.
Role of Sleep Coaching, Sleep Reset in the Care of Sleep Problems
October 6th 2023Michael Grandner, PhD, associate professor of psychiatry at the University of Arizona College of Medicine, discussed Sleep Reset, an app-based, personalized sleep program that uses sleep coaches to help guide patients in the care of their sleep disorders.
Combination Therapy Demonstrates Ability to Clear Senescent Cells in Alzheimer Disease
October 3rd 2023At the conclusion of a 12-weel treatment period, biomarker data provided mechanistic insights of senolytic effects using dasatinib and quercetin that need to be confirmed in fully powered, placebo-controlled studies.
FDA Approves Cipaglucosidase Alfa and Miglustat as First Two-Component Therapy for Pompe Disease
September 29th 2023In a phase 3 setting, the 2-component therapy showed positive trends or clinically meaningful improvements on motor and respiratory functions compared with previously approved enzyme replacement therapy.
Role of Gut Microbiome, Alpha Synuclein in the Prodromal Stage of Parkinson Disease
September 25th 2023Virginia Gao, MD, PhD, a movement disorders fellow at Weill Cornell Medicine, discussed several topics related to the use of biomarkers in the prodromal stages of neurodegenerative disorders like Parkinson disease.