Matt Hoffman

The calcitonin gene-related peptide inhibitor lowered monthly migraine days by ≥50% in 30.3% of patients compared to 13.7% on placebo.

The program seeks to optimize small-molecule compounds to decrease the production of mHtt through PTC’s splicing platform.

Using the NCT-504 compound to inhibit cell-signaling activity in PIP4Kγ resulted in an increase in autophagy in connective tissue cells from patients with HD.

Vagus nerve stimulation in conjunction with conventional rehabilitation services more than doubled lasting recovery in forelimb supination and simple motor tasks following a stroke.

Exposure to monesin has been shown to combat stress by oxidants and free radicals via the protein kinase R-like endoplasmic reticulum kinase/activating transcription factor 4 pathway.

The goal for the companies is to reach greater levels of anti-tau antibodies in a single treatment that what current weekly or bi-weekly infusions can achieve.

The FDA has expanded the approval for the Trevo clot retrieval device to allow for thrombectomy up to 24 hours after the development of symptoms in patients with acute ischemic stroke.

The injection therapy now has an indication for use in either 40 mg/mL or 20 mg/mL doses, with the lower dose having been approved in June 2015.

In a head-to-head comparison, levetiracetam was shown to increase the rate of infants free of monotherapy failure by 28% more than phenobarbital in pediatric patients with nonsyndromic epilepsy.

The smartwatch detected 40 generalized tonic-clonic seizures with 100% accuracy in a supporting clinical trial of 135 patients.

The synthetic cannabis-like therapy dronabinol was effectively used to treated patients with obstructive sleep apnea, offering a potentially better alternative to CPAP machines.

The findings reveal that taurine could be could be added to an MS therapy regimen to boost mature oligodendrocyte production, and in turn, remyelination.

A new forecast model has revealed that an additional 9 million people will develop AD over the next 40 years.