Authors
Latest:
Second Patient Dosing Recommended for TSHA-102 Gene Therapy Trial in Rett SyndromeFollowing a successful first patient treatment experience with TSHA-102, an adeno-associated virus vector-based gene therapy for Rett syndrome, Taysha Gene Therapies was recommended to continue with investigating the therapy in a second patient.
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Search for Targeted Therapies for Primary Headaches Beyond Migraine: Jihan A. Grant, MDThe director of headache medicine at The Mount Sinai Hospital talked about the often-overlooked realm of primary headaches beyond migraines as well as the importance of developing targeted treatments and increasing understanding of their pathophysiology. [WATCH TIME: 7 minutes]
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Improving Diagnosis, Screening Patients More Efficiently in Alzheimer Disease: Katherine Turk, MDThe behavioral neurologist at VA Boston Healthcare System talked about screening patients for mild cognitive impairment to improve diagnosis in Alzheimer disease at the 2023 AAN Annual Meeting. [WATCH TIME: 5 minutes]
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Practice Pearls for Management of NMOSDExperts in neurology discuss immune tolerance as an alternative strategy and share practice pearls for approaching treatment of NMOSD.
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Tools for Cultivating Meaning This Holiday SeasonWhat excites you? What awakens your sense of purpose? What gives your life meaning? Bradley McDaniels, PhD, CRC, explores the importance of meaning in one's life.
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AUPN Leadership Minute Episode 28: Leadership to Effect ChangeEpisode 28 of the AUPN Leadership Minute features Donald S. Higgins, MD, of the VHA; and Gabriele C. De Luca, MD, DPhil, FRCPath, FAAN, of University of Oxford. [WATCH TIME: 5 minutes]
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Getting Up to Speed on the Evolving Landscape of Multiple Sclerosis: Annette Okai, MDThe medical director of the North Texas Institute of Neurology and Headache offered an overview of the State of the Science Summit that was held on July 21, 2022, with a variety of expert clinicians in MS care. [WATCH TIME: 3 minutes]
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Dyskinesia: Importance of Giving Patients More Good “On- Time" in Parkinson’s DiseaseDrs Isaacson, Pahwa, and Gupta discuss the management of dyskinesia and providing good ON time in Parkinson’s disease, sharing practical tips for early identification and treatment of dyskinesia, as well as their experience with current treatments.
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Efficacy and Safety of Weekly Subcutaneous Efgartigimod for Myasthenia Gravis: Yuebing Li, MD, PhDThe neuromuscular neurologist at the Cleveland Clinic discussed findings from an analysis presented at AANEM 2023 that investigated the safety and efficacy of subcutaneous efgartigimod in patients with myasthenia gravis. [WATCH TIME: 5 minutes]
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Sleep Disturbances and Recovering From Alcohol Use Disorder: Garth T. Whiteside, PhDThe head of preclinical development at Imbrium Therapeutics provided an overview of positive safe and efficacy findings from the phase 2 study investigating sunobinop. [WATCH TIME: 4 minutes]
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Streamlining Stroke Rehab Systems in Common Clinical Care: Eric Leuthardt, MDThe founder and chief scientific officer of Neurolutions discussed complexities within the system to integrate new stroke rehab devices.
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Promising Disease-Modifying Therapies in Parkinson DiseaseDespite years of use of gold-standard therapy levodopa, therapeutic development in Parkinson disease has advanced rapidly and expanded to numerous novel pathways and targets.
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Reimaging the Approach to Treating Alzheimer Agitation: Sube Banerjee, MD, MSc, MBA, FRCPsychThe professor of dementia and executive dean of the Faculty of Health at the University of Plymouth provided perspective on the way to attack Alzheimer agitation and why drug solutions often fall short. [WATCH TIME: 3 minutes]
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Talking Transitional Readiness for Teens With Multiple Sclerosis: Vikram Bhise, MDThe associate professor of pediatrics and neurology at Rutgers–Robert Wood Johnson Medical School commented on the need to recognize when adolescent patients are ready to learn more about their condition. [WATCH TIME: 5 minutes]
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AUPN Leadership Minute Episode 39: Supporting K AwardeesEpisode 39 of the AUPN Leadership Minute features Donald S. Higgins Jr, MD, of Veterans Health Administration, Albany Medical College; and Alexandra Nelson, MD, PhD, of the University of California San Francisco. [WATCH TIME: 5 minutes]
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The Complexities of Alzheimer Disease Treatment and Diagnosis in Clinical Trials: Sharon L. Rogers, PhDThe chief executive officer at AmyriAD Therapeutics discussed the limitations of clinical trials assessing potential disease-modifying therapies for Alzhiemer disease including the lack of a diverse patient population and nonthorough clinical assessments for diagnosis. [WATCH TIME: 6 minutes]
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Utilizing a Radiotracer to Shed Light on Brain Fluid Dynamics: Mony de Leon, EdDThe director of the Brain Health Imaging Institute in the department of radiology at Weill Cornell Medicine talked about using a novel radiotracer to understand the movement of fluids and waste products in the brain. [WATCH TIME: 5 minutes]
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Ongoing Challenges for Neuromuscular and Movement Occupational Therapy: Jess Holguin, OTD, OT/LCommenting on recent advances and persistent challenges for these patients, the associate professor of clinical occupational therapy at USC Keck Hospital spoke on the need to increase equity and access to care. [WATCH TIME: 6 minutes]
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Secondary Analyses of ANNEXA-I Trial Assessing Andexanet Alfa in Intracranial Hemorrhage: Ashkan Shoamanesh, MDThe associate professor of neurology at McMaster University talked about findings from secondary analyses on the phase 4 ANNEXA-I trial assessing andexanet alfa in patients with acute intracerebral hemorrhage. [WATCH TIME: 10 minutes]
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Overcoming Language Barriers During the Diagnostic Process of Rare Neuroimmune Disorders: Paula Barreras, MDThe physician neurologist and neuroimmunologist at Cedars Sinai Medical Center detailed the difficulties with discussing neuroimmune disorders with newly diagnosed patients, including those who may not speak English. [WATCH TIME: 3 minutes]
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Cognitive Behavioral Therapy vs. Pharmacological Treatments for Insomnia: Jennifer Martin, PhDThe AASM board of directors' member and professor of medicine at UCLA discussed the benefits of CBT-I and its efficacy compared to pharmacological treatments.
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Global Impacts of Rare Disease Day for Patients With Neurologic Disorders: Jill Morris, PhDThe program director in the division of Neuroscience at the National Institute of Neurological Disorders and Stroke provided context on the importance of Rare Disease Day and strides made over the years. [WATCH TIME: 5 minutes]
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Importance of Identifying Etiology in Pediatric Stroke: Kristin Guilliams, MD, MSCIThe associate professor at Washington University School of Medicine provided commentary on the state of care for pediatric stroke, and the challenges with identifying the most likely etiology. [WATCH 3 minutes]
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Overcoming the Complexities With Gene Therapy in ALS: Anna Underhill, BSThe postdoctoral researcher at King’s College London provided background on why gene therapies have not seen as much success in treating ALS, and the need for additional validation of genetic mutations. [WATCH TIME: 3 minutes]
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Andrea Quattrone, MD: The Importance of Early Differentiation Between PSP and ParkinsonThe neurology resident at Magna Graecia University of Catanzaro also touched on how accurate early diagnoses can help hone clinical trial recruitment.
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Evaluating Therapeutic Targets for Deep Brain Stimulation in Parkinson Disease: Alfonso Fasano, MD, PhDThe professor of neurology at the University of Toronto provided insight on several prominent targets in the brain for deep brain stimulation, including emerging ones that may not gain as much attention. [WATCH TIME: 3 minutes]
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Leo Petrossian, PhD, MBA: Accelerating Optimization of Epilepsy ManagementThe CEO of Nile AI spoke to how the newly founded company plans to develop data science techniques to improve the optimization of epilepsy care and management.
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The Need for More Time in Movement Disorder Care: Temitope Lawal, MDThe neurologist and movement disorders fellow at University Hospitals Cleveland Medical Center spoke about the need for clinicians to have more time with patients in clinical practice, particularly with those with chronic diseases. [WATCH TIME: 2 minutes]
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Assessing In-Hospital Stroke Risk in Pregnant Patients Using Assisted Reproductive Technologies: Ava L. Liberman, MDThe medical director of the Stroke Center at Weill Cornell Medicine talked about results from a recent study on the risk of stroke in patients on assisted reproductive technologies during delivery hospitalization. [WATCH TIME: 4 minutes]
