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Latest:
Managing Disease Progression in MS: Changing Treatments and Clinician AdvicePanelists discuss how in multiple sclerosis (MS) treatment, clinicians must strategically evaluate disease progression, considering within-class or mechanism-of-action switches. Comprehensive monitoring, personalized approaches, and proactive management are crucial for optimizing patient outcomes and minimizing long-term neurological disability.
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Therapeutic Potential of Self-Administered Subcutaneous Rozanolixizumab in Myasthenia Gravis: Rachana K. Gandhi Mehta, MBBSThe assistant professor of neurology at Wake Forest School of Medicine provided clinical insight on MG0020, a phase 3 trial assessing a self-administration of rozanolixizumab through a syringe driver. [WATCH TIME: 3 minu]
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Evaluating Intra-Arterial Tenecteplase for Stroke: Insights From the ANGEL-TNK Trial: Xiaochuan Huo, MD, PhDThe director of the neurological disease center at Beijing Anzhen Hospital talked about assessing the potential benefits and safety of intra-arterial tenecteplase in highly selected poststroke patients. [WATCH TIME: 6 minutes]
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Turning Gene Therapy Into Reality: Peter Marks, MD, PhDThe director of the Center for Biologics Evaluation Research at the FDA provided an overview of the Keynote Address he gave at the 2023 Muscular Dystrophy Association Clinical and Scientific Conference. [WATCH TIME: 3 minutes]
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Gaining a Clearer Picture of Gene Therapy in Neuromuscular Disease: Carsten G. Bönnemann, MDThe senior investigator in the Neuromuscular and Neurogenetic Disorders of Childhood Section at NINDS shared his perspective on the data coming out of neuromuscular research and the promise of genetic medicine. [WATCH TIME: 2 minutes]
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Revisiting Deep Brain Stimulation in a Pediatric-Onset Dystonia Case: Pamela Zeilman, NPThe nurse practitioner in the Center for Movement Disorders & Neurorestoration at the University of Florida discussed a complex case of childhood-onset dystonia treated with DBS. [WATCH TIME: 6 minutes]
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Improving Post-Relapse Recovery in Multiple Sclerosis With Rehabilitation: Rachel Haines, MA, CCC-SLP, MSCS, CBISThe neuromuscular and movement disorders speech-language pathologist at Orlando Health discussed strategies in managing the phases of multiple sclerosis for patients and the need for collaborative referral practices. [WATCH TIME: 5 minutes]
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Unmet Needs in Narcolepsy and Clinical PearlsNeurology experts discuss the unmet needs in narcolepsy treatment and share clinical pearls from their experiences.
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Ongoing Therapeutic Developments for Movement Disorders: Saar Anis, MDWhen asked about developments, the neurologist and movement disorders specialist at Sheba Tel-HaShomer Medical Center in Israel commented on the need to identify disease-modifying therapies. [WATCH TIME: 3 minutes]
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Increased Risk of Epilepsy in Older Adults and the Growing Population: Alice Lam, MD, PhDThe assistant professor of neurology at Massachusetts General Hospital and Harvard Medical School spoke about the high risk of epilepsy for the older population at the 2022 AES annual meeting. [WATCH TIME: 1 minute]
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Emerging Tools for Early Detection of Alzheimer DiseaseThe field of Alzheimer disease has entered a new era of earlier detection, creating an opportunity to redefine treatment and the clinical care of patients.
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Accounting for Hormonal Factors in Traumatic Brain Injury Care for Women: Christine Greiss, DOThe medical director for the Center for Brain injuries at Hackensack Meridian Health provided recommendations for clinicians to consider in the rehabilitation of women with TBI. [WATCH TIME: 6 minutes]
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Gait Dysfunction in Parkinson Disease: The Role of the Cholinergic SystemAlthough combination carbidopa-levodopa has become a standard for the treatment of many of the motor features of PD to this day, gait dysfunction remains a difficult symptom to treat.
Latest:
The Impact of Social Participation on Cognitive Function in Patients With Parkinson Disease: Ling Wan-Albert, OTD, OTR/LThe assistant professor of occupational therapy at the New York Institute of Technology talked about educating patients with Parkinson disease about the importance of maintaining social participation for cognitive function at ATMRD 2023. [WATCH TIME: 5 minutes]
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Patient Evaluation for Excessive Daytime SleepinessExcessive daytime sleepiness is a hallmark of a number of sleep disorders, and ensuring the proper diagnosis and management of those presenting with it is crucial to care.
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Illuminating the Night: Understanding Parkinson Nighttime SymptomsLarry Gifford, a patient living with Parkinson Disease and president of the PD Avengers, discussed sleep issues and nighttime symptoms faced by millions of patients with the disease worldwide.
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Identifying Impactful Biomarkers of Alzheimer Disease: Sudhir Sivakumaran, PhD; Klaus Romero, MD, MS, FCPThe duo from the Critical Path Institute detailed the thought process behind evaluating the importance of specific biomarkers and their relation to disability progression in Alzheimer disease.
Latest:
AUPN Leadership Minute Episode 4: How to Meet With Your DeanEpisode 4 of the AUPN Leadership Minute features Clifton L. Gooch, MD, of the University of South Florida; and Robin Brey, MD, of the University of Texas Health Science Center at San Antonio. [WATCH TIME: 3 minutes]
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Clinical Benefits to Emphasizing Patient Voices in ALS: Brooke EbyA patient advocate within the ALS community discussed the importance of incorporating patients and their voices into clinical meetings and trial design to ultimately meet treatment goals. [WATCH TIME: 4 minutes]
Latest:
AUPN Leadership Minute Episode 26: Creating a Formal Junior Faculty Development PlanEpisode 26 of the AUPN Leadership Minute features Tracey A. Milligan, MD, of New York Medical College; and Larry B. Goldstein, MD, of University of Kentucky Medical Center. [WATCH TIME: 8 minutes]
Latest:
Promising Disease-Modifying Therapies in Parkinson DiseaseDespite years of use of gold-standard therapy levodopa, therapeutic development in Parkinson disease has advanced rapidly and expanded to numerous novel pathways and targets.
Latest:
AUPN Leadership Minute Episode 10: What Your CEO Wants From YouEpisode 10 of the AUPN Leadership Minute features Mud M Alvi, MD, of West Virginia University and Robert C. Byrd Health; and Albert L. Wright, Jr., the president and CEO of West Virginia University Health System. [WATCH TIME: 4 minutes]
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Emerging Agents in Alzheimer’s DiseasePanelists discuss how emerging therapeutic targets, including amyloid-beta plaques, tau protein aggregation, inflammation modulation, and mitochondrial dysfunction, offer promising approaches for disease-modifying treatments in early Alzheimer's disease.
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Advice to Physicians for Use of Wearable Devices in PDZoltan Mari, MD, shares advice and tips to physicians and patients for the use of wearable devices in PD.
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Cluster Headache: A Clinical OverviewAs the most common trigeminal autonomic cephalalgia, this unilateral and severe headache is accompanied by ipsilateral autonomic features and is often challenging to treat.
Latest:
CoMPoSER, Developing a Music-Based Sleep App for Patients With Dementia and Caregivers: Darina Petrovsky, PhD, RNThe assistant professor at Duke University School of Nursing talked about a project aimed at developing a music-based mobile app to improve sleep for individuals with dementia and their caregivers. [WATCH TIME: 5 minutes]
Latest:
Building a Greater Knowledge on Use of SMA Therapies: Thomas Crawford, MDThe pediatric neurologist at Johns Hopkins Medicine provided commentary on the steps needed to improve treatment optimization in SMA, and the unanswered questions regarding the key biology of the disease.
Latest:
AUPN Leadership Minute Episode 3: Teaching Millennial Medical StudentsEpisode 3 of the AUPN Leadership Minute features Rohit Das, MD, of University of Texas Southwestern Medical Center at Dallas; and Mehmood Rashid, MD, of University of Toledo. [WATCH TIME: 4 minutes]
Latest:
Recognizing the Clinical Features of MOGAD for Diagnosis: Eoin P. Flanagan, MB, BChThe professor of neurology at Mayo Clinic talked about how MOG antibody-associated disease can be diagnosed through specific antibody tests, highlighting its distinct clinical and MRI features. [WATCH TIME: 4 minutes]
