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Key Considerations in Treatment of Spinal Muscular Atrophy / Considerações essenciais para o tratamento da atrofia muscular espinhalThe expert panel shares clinical pearls for treatment and management of Spinal Muscular Atrophy. O painel de especialistas compartilha recomendações valiosas para o tratamento e manejo da atrofia muscular espinhal.
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Future Treatment of hATTR AmyloidosisAnalysis of current and newer therapies for the treatment of hereditary ATTR amyloidosis.
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The Partnership Between MT2020+ and Medtronic: Dileep Yavagal, MD, and Dan VolzThe professor of clinical neurology at University of Miami and MT2020+ chair, and president of Medtronic's Neurovascular Business discussed the effort to improve global accessibility of mechanical thrombectomy.
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Expanding the Capabilities of Treating Neuromuscular Poststroke Symptoms: Wayne Feng, MD, FAHAThe division chief of stroke and vascular neurology at Duke Health provided perspective on the multidisciplinary team needed to treat neuromuscular poststroke symptoms, as well as exciting innovations on the horizon. [WATCH TIME: 4 minutes]
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Rare Reactions With Natalizumab Infusion: Yujie Wang, MDThe neurologist from the University of Washington Medical Center discussed the findings of her recent study presented at ACTRIMS Forum 2021.
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Regulatory Outlook for Atogepant in Migraine: Lawrence Severt, MD, PhDThe director at AbbVie discussed the timeline for when a regulatory decision may come for migraine treatment atogepant, and whether additional trials are necessary.
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New Treatments in Migraine: An In-Depth ReviewAlthough new treatments and innovations are a sign of growth in migraine care, it is important to realize that growth comes with a certain amount of pain. In clinical practice, choosing the right treatment option for patients in a time-limited visit is often a dilemma.
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Ongoing Clinical Trials and the Future of ALSKey opinion leaders review the study design and mechanisms of action for drugs in ongoing clinical trials and consider the future of amyotrophic lateral sclerosis (ALS).
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Optimizing Mobile Stroke Units and Dealing With Associated Costs: Gregory W. Albers, MDThe director of the Stanford Stroke Center and Coyote Foundation Professor of Neurology and Neurological Sciences at Stanford Medical Center shared his perspective on the uptake of mobile stroke units across the United States. [WATCH TIME: 6 minutes]
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Sustainability and Future of Intermittent Calorie Restriction in Multiple Sclerosis: Laura Piccio, MD, PhDThe neurologist and physician scientist at Washington University in St. Louis provided perspective on the need for additional studies assessing the long-term effects of dieting strategies in multiple sclerosis. [WATCH TIME: 3 minutes]
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Future Direction of AI, Neuroimaging Research: Michael Dwyer, PhDThe director of IT and Neuroinformatics Development at the Buffalo Neuroimaging Analysis Center discussed future neuroimaging projects the center is evaluating and where the focus turns to next. [WATCH TIME: 3 minutes]
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The Potential and Limitations of AI Algorithms in Sleep Care: Anuja Bandyopadhyay, MDThe assistant professor of clinical pediatrics at Indiana University School of Medicine, and the chair of the AASM’s Artificial Intelligence in Sleep Medicine Committee, spoke about the ability of AI algorithms as tools in clinical care. [WATCH TIME: 3 minutes]
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Addressing US Preventive Services Task Force Aspirin Recommendations for StrokeIn a time when complex medical communication to the public is on display, the need to ensure patient comprehension is of utmost importance for vascular neurologists.
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Physical Therapy Approach for Fatigue Management in Multiple SclerosisFatigue, although not immediately visible, is among the most debilitating symptoms of multiple sclerosis, affecting not only patients' day-to-day functioning but their quality of life.
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Newborn Screening Awareness Month: Understanding the Impact of Newborn Screening for SMAAdvocacy organization Cure SMA provides insight on the importance of continuing to push for standardized newborn screening and how it can positively impact outcomes in SMA.
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MDA’s Focus on Better Access for Patients With Neuromuscular Disorders: Paul MelmeyerAhead of the 2023 MDA Conference, which will be held from March 19-22, 2023, in Dallas, Texas, the vice president of public policy and advocacy at the Muscular Dystrophy Association provided an overview of the current state of access and the need for more advocates in neuromuscular disease. [WATCH TIME: 14 minutes]
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Sudden Unexpected Death in Epilepsy Linked With Sleep: Sanjeev Kothare, MDThe division director of pediatric neurology, and director of the pediatric sleep program at Cohen, Children's Medical Center, Northwell Health, spoke about sudden unexpected death in epilepsy and sleep at the 2022 AES Conference. [WATCH TIME: 3 minutes]
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Reactions to FDA Advisory Panel Decision on AMX0035: Justin Klee; Josh Cohen, BScThe co-CEOs and co-founders of Amylyx Pharmaceuticals discussed their immediate thoughts to the recent FDA AdComm meeting, which voted against evidence of efficacy for AMX0035 in ALS. [WATCH TIME: 3 minutes]
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The Need for Education on Advanced Therapeutics for Movement Disorders: Fernando Pagan, MD; Yasar Torres-Yaghi, MDThe duo from MedStar Georgetown University Hospital detailed the need for education on Parkinson disease and movement disorder therapies, and the CME activities they’ve developed with the PMD Alliance to address those needs. [WATCH TIME: 5 minutes]
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Greatest Challenges in Repurposing Alzheimer Drugs: Feixiong Cheng, PhDThe assistant professor at Cleveland Clinic provided thoughts on the barriers clinicians face when formulating and conducting Alzheimer disease clinical trials with repurposed drugs.
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AUPN Leadership Minute Episode 24: How Much Is a Neurologist Worth: Factoring the DownstreamEpisode 24 of the AUPN Leadership Minute features Alissa Willis, MD, of University of Mississippi Medical Center; and Joseph R. Berger, MD, of the University of Pennsylvania. [WATCH TIME: 7 minutes]
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Virendra Mishra, PhD: Previous Data on Parkinson Disease DementiaThe Cleveland Clinic researcher discussed the unknowns about Parkinson disease dementia and what has been previously observed in clinical studies.
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Identifying Impactful Biomarkers of Alzheimer Disease: Sudhir Sivakumaran, PhD; Klaus Romero, MD, MS, FCPThe duo from the Critical Path Institute detailed the thought process behind evaluating the importance of specific biomarkers and their relation to disability progression in Alzheimer disease.
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Effects of Combination Therapies, Treatment Adverse Effects in Myasthenia Gravis: Nicholas Silvestri, MD, FAANThe clinical professor at the University at Buffalo discussed the complexities of using combination therapies to treat myasthenia gravis, and whether adverse events play a major role in treatment decisions. [WATCH TIME: 3 minutes]
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Understanding Race-Gender Associations in Insomnia Patterns and Late-Life Memory Trajectories: Afsara ZaheedThe graduate student at the University of Michigan provided insight on her study examining longitudinal patterns of difficulty initiating sleep and their associations with subsequent memory trajectories among different races and genders. [WATCH TIME: 3 minutes]
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Unmet Needs and Advice for the Management of OFF Episodes in Parkinson DiseaseExpert neurologists provide insight on unmet needs, challenges to improve access to care, and highlight clinical pearls for the management of OFF episodes in Parkinson disease.
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Expanding Research on MS Diagnosis Disclosure and Long-Term Impacts: Anne Kever, PhDThe postdoctoral researcher at Columbia University discussed the long-term plans to gain a better understanding of MS diagnosis disclosure and how it can impact other qualities of life.
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Future Aspirations of Neonatal Seizure Research: Solomon Moshe, MD; Elissa Yozawitz, MDThe duo from Montefiore Medical Center discussed aspects of their recently published recommendations on neonatal seizure diagnosis that need further examining.
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Advice for Managing MSJoseph R. Berger, MD, and Fred D. Lublin, MD, offer advice to community physicians and neurologists in managing patients with multiple sclerosis.
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A New Approach to Communicating Hydrocephalus: An Overdue OpportunityA pair of cerebrovascular and neurosurgery experts discuss a novel approach to communicating hydrocephalus with an arachnoid granulation using a miniature implant, delivered via a percutaneous endovascular catheter.
