Authors
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Regulatory Outlook for Atogepant in Migraine: Lawrence Severt, MD, PhDThe director at AbbVie discussed the timeline for when a regulatory decision may come for migraine treatment atogepant, and whether additional trials are necessary.
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New Treatments in Migraine: An In-Depth ReviewAlthough new treatments and innovations are a sign of growth in migraine care, it is important to realize that growth comes with a certain amount of pain. In clinical practice, choosing the right treatment option for patients in a time-limited visit is often a dilemma.
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Caregiving Youth: A Call to Action for Improved SupportA systematic approach to understanding the needs of the caregiving youth—a growing and less-studied population of caregivers—is needed to better tailor interventions, provide support, and improve care to patients and their families.
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Optimizing Localization in Multiple Sclerosis Diagnosis: Aliza Ben-Zacharia, PhD, DNP, ANP-BC, FAANThe assistant professor at Hunter College talked about the approach of localization to prevent misdiagnoses of multiple sclerosis and ensure patients receive appropriate treatment. [WATCH TIME: 3 minutes]
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Ongoing Clinical Trials and the Future of ALSKey opinion leaders review the study design and mechanisms of action for drugs in ongoing clinical trials and consider the future of amyotrophic lateral sclerosis (ALS).
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Safely Expanding the Time Window of Thrombolysis: Gregory W. Albers, MDThe professor of neurology and director of the Stanford Stroke Center discussed the ways stroke care is evolving and the significance of the TIMELESS trial, which demonstrated the safety of tenecteplase in later-window poststroke patients. [WATCH TIME: 7 minutes]
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Applying the Innovation Biodesign Framework to Promote Equity and Green Activity in Dementia CareLassell et al present a use case demonstrating the process of moving an unmet need to the “solution space” of the Innovation Biodesign Framework for addressing a healthcare challenge in a specific at-risk population: Alzheimer disease and AD-related dementias.
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Sustainability and Future of Intermittent Calorie Restriction in Multiple Sclerosis: Laura Piccio, MD, PhDThe neurologist and physician scientist at Washington University in St. Louis provided perspective on the need for additional studies assessing the long-term effects of dieting strategies in multiple sclerosis. [WATCH TIME: 3 minutes]
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AI in Multiple Sclerosis: Expert Insights Into Limitations and OpportunitiesExperts share insights on the latest innovations in multiple sclerosis research, in highlights from a recent State of the Science SummitTM, presented by Neurology Live®.
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The Potential and Limitations of AI Algorithms in Sleep Care: Anuja Bandyopadhyay, MDThe assistant professor of clinical pediatrics at Indiana University School of Medicine, and the chair of the AASM’s Artificial Intelligence in Sleep Medicine Committee, spoke about the ability of AI algorithms as tools in clinical care. [WATCH TIME: 3 minutes]
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Treating Trigeminal Neuralgia With Stereotactic Radiosurgery via CyberKnife: David Huang, MDThe radiation oncologist at Cooperman Barnabas Medical Center talked about how trigeminal neuralgia can be effectively treated with stereotactic radiosurgery using the CyberKnife offering pain relief without the need for invasive surgery. [WATCH TIME: 6 minutes]
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Addressing US Preventive Services Task Force Aspirin Recommendations for StrokeIn a time when complex medical communication to the public is on display, the need to ensure patient comprehension is of utmost importance for vascular neurologists.
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Impact of Blood Tests on Wait Times and Treatment in Alzheimer Disease: Soeren Mattke, MD, DScThe director of the Brain Health Observatory at the University of Southern California discussed how blood tests for Alzheimer disease could significantly reduce diagnostic wait times and improve treatment monitoring. [WATCH TIME: 4 minutes]
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Lessons from a Multiple Sclerosis Feasibility Study Focused on Movement Medicine: Afolasade Fakolade, PhDThe assistant professor at Queen’s University discussed results from a pilot trial that evaluated the impact of a dyadic physical activity intervention among both caregivers and patients with multiple sclerosis. [WATCH TIME: 3 minutes]
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AUPN Leadership Minute Episode 37: International Physicians in NeurologyEpisode 37 of the AUPN Leadership Minute features David G. Standaert, MD, PhD, of the University of Alabama at Birmingham; and Erica A. Schuyler, MD, of the University of Connecticut. [WATCH TIME: 5 minutes]
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A Provider's Cheat Sheet Guide to Understanding SleepSleep is critical for physical and mental health, with its insufficiency leading to various disorders and increased health risks; thus, clinicians should integrate sleep assessments and hygiene strategies into their clinical care.
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Physical Therapy Approach for Fatigue Management in Multiple SclerosisFatigue, although not immediately visible, is among the most debilitating symptoms of multiple sclerosis, affecting not only patients' day-to-day functioning but their quality of life.
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The Potential of Genetic Therapies in Neuromuscular Diseases: Stephan Züchner, MD, PhDAt the 2023 MDA conference, the professor for human genetics and neurology at the University of Miami Miller School of Medicine talked about the role of genetics in neuromuscular diseases and potential therapies. [WATCH TIME: 5 minutes]
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Newborn Screening Awareness Month: Understanding the Impact of Newborn Screening for SMAAdvocacy organization Cure SMA provides insight on the importance of continuing to push for standardized newborn screening and how it can positively impact outcomes in SMA.
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The Significance of Gene Therapy in Neuromuscular Medicine at the 2025 MDA Conference: Paul Melmeyer, MPPPrior to the 2025 MDA Conference, the vice president of Public Policy & Advocacy at the Muscular Dystrophy Association talked about the increasing interest in gene therapy in the field of neuromuscular diseases.
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Sudden Unexpected Death in Epilepsy Linked With Sleep: Sanjeev Kothare, MDThe division director of pediatric neurology, and director of the pediatric sleep program at Cohen, Children's Medical Center, Northwell Health, spoke about sudden unexpected death in epilepsy and sleep at the 2022 AES Conference. [WATCH TIME: 3 minutes]
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Reactions to FDA Advisory Panel Decision on AMX0035: Justin Klee; Josh Cohen, BScThe co-CEOs and co-founders of Amylyx Pharmaceuticals discussed their immediate thoughts to the recent FDA AdComm meeting, which voted against evidence of efficacy for AMX0035 in ALS. [WATCH TIME: 3 minutes]
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Nuances in Thrombectomy Techniques and Anesthesia Use for Stroke: J Mocco, MD, MSThe director of the Cerebrovascular Center at Mount Sinai discussed how results from the ESCAPE-MeVO trial highlight the impact of anesthesia rates, thrombectomy techniques, and the need for rigorous clinical trials to minimize bias. [WATCH TIME: 3 minutes]
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Reasons to Attend the 2023 Advanced Therapeutics in Movement & Related Disorders Congress: Fernando Pagan, MD; Yasar Torres-Yaghi, MDThe course directors of the 2023 ATRMD Congress provided an overview of the upcoming meeting, and the educational benefits clinicians can gain from attending. [WATCH TIME: 6 minutes]
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Understanding the Microglial Immunologic Sex Differences in Alzheimer Disease: Feixiong Cheng, PhDThe assistant professor at Cleveland Clinic discussed findings from a recently published study that provided insights on the understanding of the molecular basis for female predominance in Alzheimer disease. [WATCH TIME: 3 minutes]
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AUPN Leading Edge Episode 4: How Much Is a Neurologist Worth? Factoring the DownstreamAUPN Leading Edge Episode 4 features Rohit Das, MD, and Joseph R. Berger, MD, who discuss how neurologists are undervalued in academic and non-academic settings when their compensation is predicated on RVUs alone. [LISTEN TIME: 26 minutes]
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Limitations of Advanced Parkinson Disease TreatmentsPanelists discuss how limitations persist with current long-term treatment standards for Parkinson disease despite advancements in treatment options.
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Virendra Mishra, PhD: Previous Data on Parkinson Disease DementiaThe Cleveland Clinic researcher discussed the unknowns about Parkinson disease dementia and what has been previously observed in clinical studies.
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Building a Greater Knowledge Profile of Sodium Oxybate Treatment for Narcolepsy: Phil Jochelson, MDThe therapeutic head for Clinical Development Neuroscience at Jazz Pharmaceuticals discussed how sodium oxybate has evolved over the years and the educational aspects of cardiovascular implications patients and clinicians should be aware of. [WATCH TIME: 3 minutes]
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Identifying Impactful Biomarkers of Alzheimer Disease: Sudhir Sivakumaran, PhD; Klaus Romero, MD, MS, FCPThe duo from the Critical Path Institute detailed the thought process behind evaluating the importance of specific biomarkers and their relation to disability progression in Alzheimer disease.
