Authors

Potential of Advancing Neurofibromatosis Care With Investigational Mirdametinib

Jim Cassidy, MD, PhD, chief medical officer at SpringWorks Therapeutics, talked about how the prioritization of mirdametinib, a promising treatment for both adult and pediatric patients with neurofibromatosis type 1-associated plexiform neurofibromas.

Looking Ahead: How Consensus Guidelines Will Shape the Future of SMA Care

This closing episode looks ahead to the future of SMA care, examining how updated best practices aim to accelerate access, optimize outcomes, and fuel ongoing progress.

NeuroVoices: Mitch Elkind, MD, MS, FAHA, on Enhancing Brain Health Amid World Stroke Day

The chief science officer at the American Heart Association discusses its priorities for stroke prevention, cross-specialty collaboration, and equitable care as clinicians mark World Stroke Day 2025.

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Rare Diseases Are More Common Than Their Name May Imply

Caroline Just, MD, reflects on the challenges of diagnosing and treating rare neurological diseases, urging for improved education, collaboration, and research efforts.

A New Approach to Communicating Hydrocephalus: An Overdue Opportunity

A pair of cerebrovascular and neurosurgery experts discuss a novel approach to communicating hydrocephalus with an arachnoid granulation using a miniature implant, delivered via a percutaneous endovascular catheter.

COVID-19 Shutdowns and the Disruption to Deep Brain Stimulation Treatment

While shutdowns disrupted care for all patients with Parkinson disease, hospitals were forced to postpone elective procedures such as the initial DBS device implantation and implantable pulse generator replacements.

Digital Health Tool Offers Innovative Quantitative Fall Assessment Solution for Older Adults

Falls cost the US more than $50 billion annually, but platforms like CatchU, a transformative digital health tool, provide quantitative fall assessment that might significantly enhance the current standard of care for predicting falls.

A Practical Approach to Chronic Immunosuppression in Myasthenia Gravis

A practical approach to initiating and tapering corticosteroids, and the considerations in the selection and monitoring parameters of steroid-sparing agents are crucial to the care of myasthenia gravis.

Applying the Innovation Biodesign Framework to Promote Equity and Green Activity in Dementia Care

Lassell et al present a use case demonstrating the process of moving an unmet need to the “solution space” of the Innovation Biodesign Framework for addressing a healthcare challenge in a specific at-risk population: Alzheimer disease and AD-related dementias.

The Complement Connection in Guillain-Barre and Chronic Inflammatory Demyelinating Polyneuropathy

Explore the role of the complement system in autoimmune neuropathies like GBS and CIDP, and discover innovative therapeutic strategies targeting complement pathways.

Insights on Quanterix Simoa Assay to Diagnose Alzheimer Disease: Mark Roskey, PhD

The chief scientific officer at Quanterix gave a clinical overview on how the company’s Simoa platform enables ultrasensitive detection of neurodegeneration biomarkers in blood, transforming Alzheimer and Parkinson disease research. [WATCH TIME: 3 minutes]

Filling in the Care Management Gaps for Parkinson Disease With Software Technologies

StrivePD and Apple Watch continuously track motor symptoms, aiding neurologists in adjusting treatments for better patient outcomes.

Implementing Headache Training in Residency

Despite a tremendous burden regarding migraine-related disability and expenditure, headache disorders remain underdiagnosed and undertreated, and only a small percentage of patients report satisfaction with the treatment received.

CAR-T Cell Therapy: Firing Up the Engines as a Possible B-Cell Directed Treatment for MS

Known for his expertise in stem cell transplantation, Cleveland Clinic researcher Jeffrey Cohen, MD, shifted gears to discuss other cell-based therapies in his Whitaker Lecture at the CMSC Annual Meeting.

A Rationale and Step-by-Step Strategy for Including Care Partners in MS Care

Engaging care partners in multiple sclerosis treatment enhances patient outcomes and supports their well-being, fostering healthier care partnerships.

A Doctor Celebrates the Role of Nurse Practitioners in Providing the Highest Caliber Care

Heidi Schwarz, MD, offers her perspective on the role of advanced practice providers in clinical neurological care and the benefit that they provide to practices.

Promise and Challenges of Targeting PACAP to Treat Migraine: Michael Marmura, MD

The director of outpatient care at Jefferson Headache Center weighed in on the future of PACAP as a migraine target and previewed upcoming innovations at the 2025 AHS Annual Meeting. [WATCH TIME: 3 minutes]

ChatGPT: A Promising Tool to Combat Social Isolation and Loneliness in Older Adults With Mild Cognitive Impairment

Recent advances in artificial intelligence—particularly conversational AI tools such as ChatGPT—suggest promising potential in addressing the issues of loneliness and social isolation in these patient populations.

Patient and Clinical Perspectives on Advancing MS Care Through Treatment, Advocacy, and Research

A patient and neurologist discussed personal and professional perspectives on treatment initiation, ongoing research, and patient advocacy in multiple sclerosis. [WATCH TIME: 5 minutes]

The State of Biomarkers in Multiple Sclerosis

As the field of MS care turns its sights on addressing progressive disease, the need for more biomarkers of disease activity and therapeutic target engagement is perhaps greater than ever.

Yale Researchers Shed Light on Epigenetic Differences in Patients with Syphilis and Neurosyphilis

Stroke Intervention: A New Application of Interventional Neuroradiology

New training pathways are needed to close the gap between capable-physician supply and the growing demand for thrombectomy.

Swallow This: Treating Dysphagia with Speech Pathology

Stephanie Richardson, MS, CCC-SLP, an outpatient lead speech-language pathologist at Brooks Rehabilitation, discussed the unique aspects of speech therapy and the pivotal role it plays in helping patients with swallowing and other related functions.