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NeurologyLive® Friday 5 — May 30, 2025

Key Takeaways

  • PBGENE-DMD shows potential as a one-time gene-editing therapy targeting dystrophin mutations in Duchenne Muscular Dystrophy.
  • Imlifidase demonstrates promising phase 2 safety and efficacy data in Guillain-Barré Syndrome, with a targeted, fast-acting mechanism.
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Take 5 minutes to catch up on NeurologyLive®'s highlights from the week ending May 30, 2025.

Welcome to NeurologyLive®'s Friday 5! Every week, the staff compiles 5 highlights of NeurologyLive's widespread coverage in neurology, ranging from newsworthy study findings and FDA action to expert interviews and peer-to-peer panel discussions.

1: Tracking Therapeutic Progress of Gene-Editing Agent PBGENE-DMD for Duchenne Muscular Dystrophy

Jeff Smith, PhD, chief executive officer at Precision Biosciences, explained the clinical potential and gene-editing mechanism of PBGENE-DMD, a one-time therapy targeting dystrophin mutations in Duchenne muscular dystrophy.

Tracking Therapeutic Progress of Gene-Editing Agent PBGENE-DMD for Duchenne Muscular Dystrophy

2: Overviewing Phase 2 Data of Imlifidase in Guillain-Barré Syndrome: Elisabeth Sonesson, PhD

The vice president and franchise lead of Autoimmune at Hansa Biopharma provided clinical insights on latest phase 2 safety and efficacy data on imlifidase, an IgG-cleaving antibody, in Guillain-Barré syndrome. [WATCH TIME: 3 minutes]

Overviewing Phase 2 Data of Imlifidase in Guillain-Barré Syndrome: Elisabeth Sonesson, PhD

3: Holistic Strategies and to Promote Remyelination in MS

In this roundtable episode, neurologists Paul Tesar, PhD, and Ari Green, MD, examine the plausibility, limitations, and risks of holistic approaches to remyelination—and what patients should prioritize or avoid.

Holistic Strategies and to Promote Remyelination in MS

4: NeuroVoices: Elisabeth Sonesson, PhD, on Imlifidase’s Targeted, Fast-Acting Approach to GBS

The vice president and franchise lead of Autoimmune at Hansa Biopharma shed insights on imlifidase’s targeted mechanism and promising phase 2 data in treating Guillain-Barré syndrome.

NeuroVoices: Elisabeth Sonesson, PhD, on Imlifidase’s Targeted, Fast-Acting Approach to GBS

5: Screening and Managing Comorbidities for Patients With Duchenne Muscular Dystrophy

In this NeurologyLive Insights episode, Diana Castro, MD, explores the comprehensive comorbidities of Duchenne Muscular Dystrophy, including cognitive, respiratory, and nutritional challenges faced by patients.

Screening and Managing Comorbidities for Patients With Duchenne Muscular Dystrophy

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