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Alzheimer's Association International Conference

The Alzheimer’s Association International Conference (AAIC) is the largest international meeting dedicated to advancing dementia science. It convenes basic science and clinical researchers, next-generation investigators, clinicians, and the research community to share research discoveries toward preventing and treating Alzheimer disease.

Incorporating Voice Analytics Into Cognitive Assessments: Alvaro Pascual-Leone, MD, PhD

August 07, 2022

The chief medical officer and cofounder of Linus Health provided insight on the outlook of acoustic measures and machine learning to further classify cognitive impairment. [WATCH TIME: 4 minutes]

Using Initial Cognitive Symptoms to Predict Trajectories of Neurodegenerative Pathologies

August 06, 2022

Jagan A. Pillai, MD, PhD, neurologist, Cleveland Clinic Lou Ruvo Center for Brain Health, discussed a recent study which found faster clinical progression in those with nonamnestic initial cognitive symptoms.

Risk of Incident Dementia Influenced by Apathy, Cognitive Status, and APOE Genotype in Mild Behavioral Impairment

August 05, 2022

Effect modification by cognitive status and APOE genotype revealed greater effects of mild behavioral impairment with apathy in those who had normal cognition or in non-APOE ɛ4 groups.

Understanding the Neuropathological Link Between Preeclampsia and Neuroinflammation, Neurovascular Damage: Vesna Garovic, MD, PhD

August 05, 2022

The nephrologist at Mayo Clinic provided insight on new data showing elevated extracellular vesicles of neurovascular origin in women with a history of severe preeclampsia years after pregnancy. [WATCH TIME: 4 minutes]

Using Nonamnestic Cognitive Symptoms to Predict Trajectories of Neurodegenerative Disorders: Jagan A. Pillai, MD, PhD

August 04, 2022

The neurologist at Cleveland Clinic’s Lou Ruvo Center for Brain Health detailed new findings on whether initial cognitive symptoms have similar rates of functional decline across a handful of neurodegenerative disorders. [WATCH TIME: 3 minutes]

Plasma Neurofilament Light Levels Predict Poor Memory and Cognition, But Not Sleep, in Prodromal Alzheimer Stages

August 04, 2022

In addition to significant associations between executive memory and cognition, baseline neurofilament light levels and age trended toward significance.

Formulating the Right Combination of Acoustic Metrics to Quantify Cognitive Impairment: Alvaro Pascual-Leone, MD, PhD

August 03, 2022

The chief medical officer and cofounder of Linus Health provided background on the reasoning for the measures used in a new machine learning algorithm that classifies cognitive status. [WATCH TIME: 3 minutes]

AAIC Expert Insight: Can Alzheimer Disease Be Treated With a Single-Target Approach?

August 03, 2022

During a Focused Topic Session at the 2022 Alzheimer’s Association International Conference, NeurologyLive® inquired with a panel of experts about the possibility of exploring a combination approach to Alzheimer disease as the future of treatment.

Cognition and Fall Risk Improved in Alzheimer Disease Following Exercise Program

August 03, 2022

All severities of Alzheimer disease showed statistically significant benefits from the exercise program relative to controls, with more mild groups demonstrating the most improvement.

Crenezumab Fails to Meet Primary End Points in API ADAD Colombia Trial

August 02, 2022

The monoclonal antibody that preferentially targets Aß oligomers failed to meet either of its coprimary end points—despite favorable results over the placebo group—in individuals who were unimpaired but at risk for AD.