The Alzheimer’s Association International Conference (AAIC) is the largest international meeting dedicated to advancing dementia science. It convenes basic science and clinical researchers, next-generation investigators, clinicians, and the research community to share research discoveries toward preventing and treating Alzheimer disease.
AAIC Expert Insight: Can Alzheimer Disease Be Treated With a Single-Target Approach?
August 3rd 2022During a Focused Topic Session at the 2022 Alzheimer’s Association International Conference, NeurologyLive® inquired with a panel of experts about the possibility of exploring a combination approach to Alzheimer disease as the future of treatment.
Crenezumab Fails to Meet Primary End Points in API ADAD Colombia Trial
August 2nd 2022The monoclonal antibody that preferentially targets Aß oligomers failed to meet either of its coprimary end points—despite favorable results over the placebo group—in individuals who were unimpaired but at risk for AD.
Rare Missense Variant of APOE Shows Increased Risk of Alzheimer Disease in African Ancestry
August 2nd 2022Using several large-scale cohorts, findings showed that cumulative incidence of Alzheimer disease grows faster with age in R145C variant carriers compared with noncarriers, contradicting prior research results.
Positive Life Change During Pandemic Linked to Fewer Cognitive Symptoms Among Latin American Elderly
July 31st 2022A cohort of more than 2000 older Latin American individuals reported a significant difference in cognitive symptoms when they underwent a positive life change during the early phase of the COVID-19 pandemic.
Fosgonimeton Fails to Reach End Points, but Shows Mechanistic Potential in Alzheimer Disease
June 23rd 2022After 26 weeks of treatment, those on fosgonimeton alone without acetylcholinesterase inhibitors showed a potentially beneficial change in event-related potential P300 latency, an outcome of working memory processing speed.
NeuroVoices: James Galvin, MD, MPH, on Location and Greenhouse Space Effects on Alzheimer Risk
August 18th 2021The director of the Comprehensive Center for Brain Health at the University of Miami Miller School of Medicine provided context on greenhouse spaces and their preventive benefits in Alzheimer disease.
Associations Between Greenspace and Cognitive Performance: James E. Galvin, MD, MPH
August 16th 2021The director of the Comprehensive Center for Brain Health at the University of Miami Miller School of Medicine discussed the clinical significance of his findings on neighborhood tree canopy and brain health.