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Case-Based Insights: Expert Perspectives on the Treatment of Adult-Onset SMA

Expert neurologists discuss patient cases involving the treatment of adult-onset spinal muscular atrophy (SMA).

EP. 1: A 28-Year-Old Male With SMA

July 23rd 2021

Arun S. Varadhachary, MD, PhD provides an overview of the case of a 28-year-old male with spinal muscular atrophy, describes the 4 main phenotypes of SMA, and considers how average age of onset impacts patient prognosis.

EP. 2: The Importance of Early Diagnosis of SMA

July 23rd 2021

An expert neurologist, Arun S. Varadhachary, MD, PhD considers the diagnostic process for SMA and emphasizes the importance of early diagnosis to optimize care.

EP. 3: A 38-Year-Old Female with Spinal Muscular Atrophy

July 23rd 2021

James Wymer, MD, provides a case overview of a 38-year-old female diagnosed with spinal muscular atrophy.

EP. 4: Diagnosis of Adult-Onset SMA

July 23rd 2021

An overview of the diagnosis of spinal muscular atrophy, including prevalence, age of onset, and the role of genetic testing.

EP. 5: A Multidisciplinary Approach to Managing SMA

July 30th 2021

A key opinion leader in neurology highlights the value of a multidisciplinary approach to care for patients with spinal muscular atrophy in order to maximize a patient’s function through physical and medical therapy.

EP. 6: The Safety and Efficacy of Nusinersen for SMA

July 30th 2021

A specialist in the care of patients with spinal muscular atrophy reviews the CHERISH trial of nusinersen and examines the drug’s safety and efficacy profiles.

EP. 7: Treatment Approach in SMA

July 30th 2021

A discussion of the multidisciplinary treatment approach in spinal muscular atrophy.

EP. 8: Goals of Therapy and Treatment Selection in Adult-Onset SMA

July 30th 2021

An insight into the goals of therapy and treatment selection between oral and intrathecal medications for adult-onset spinal muscular atrophy.

EP. 9: Unmet Needs and the Future of SMA Care

August 6th 2021

Arun S. Varadhachary, MD, PhD shares insights into clinicians’ and patients’ experiences with medical therapy, comments on unmet needs for adult patients, and speculates about the future of SMA care.

EP. 10: Importance of Compliance and Multidisciplinary Management in SMA

August 6th 2021

An expert neurologist emphasizes the importance of medication compliance and the value of multidisciplinary management in meeting patient goals of therapy for spinal muscular atrophy.