Peer Exchange

  

Understanding Hereditary ATTR (hATTR) Amyloidosis and the Recent Advances in Management


Key insight surrounding issues concerning the diagnosis and management of patients with hereditary ATTR amyloidosis.

Insight regarding current rates of prevalence of hereditary ATTR amyloidosis and advice to help clinicians more appropriately diagnose the condition earlier.

Red-flag symptoms and the role of a patient’s family history in diagnosing hereditary ATTR amyloidosis.

Considerations for diagnosing patients with hereditary ATTR amyloidosis who may present with rarer cases.

Diagnostic criteria commonly used to help ensure an accurate diagnosis of hereditary ATTR amyloidosis.

Recommendations for pursuing a tissue biopsy to help identify and manage hereditary ATTR amyloidosis.

Important considerations surrounding the diagnosis of hereditary ATTR amyloidosis with cardiomyopathy.

Expert panelists explore the applicability of additional testing procedures sometimes used to help diagnose hereditary ATTR amyloidosis.

Recommendations for gene panel testing with genetic counseling to evaluate and manage patients with hereditary ATTR amyloidosis.

Insight regarding the relationship between amyloid deposition and its impact on the gastrointestinal tract.

A historical overview of the treatment of hereditary ATTR amyloidosis and considerations for using newer therapies such as patisiran or inotersen in appropriate patients.

Expert clinicians elaborate on key trial data revealed through the APOLLO and NEURO-TTR studies in hereditary ATTR amyloidosis.

Considerations for transplantation in the era of newer therapies for the treatment of hereditary ATTR amyloidosis.

Unmet needs based on current trial data and treatment indications for hereditary ATTR amyloidosis.

Key opinion leaders explore the current and future role of therapies for the treatment of hereditary amyloid transthyretin amyloidosis.

Unmet needs surrounding the diagnostic work-up of patients with hereditary amyloid transthyretin amyloidosis and recommendations for biomarkers to help inform on treatment.
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