Advances in Treatment of Agitation Associated with Dementia Due to Alzheimer Disease

0:00:00 Introduction

0:01:21 The definition and prevalence of agitation in Alzheimer’s disease

0:05:17 The International Psychogeriatric Association Agitation Workgroup agitation reduction and prevention psychogeriatric consensus algorithm

0:07:00 Episodic agitation

0:09:57 The pathophysiology of agitation

0:09:52 Diagnostic work up in agitation

0:13:15 Managing agitation in long term care facilities

0:15:54 The burden of agitation

0:17:52 Nonpharmacological treatment options

0:20:49 Pharmacological treatment options

0:22:32 Brexpiprazole for treatment of agitation

0:23:17 Mechanism of action and clinical trial data of brexpiprazole

0:25:40 Safety profile of brexpiprazole

0:26:58 Managing expectations with brexpiprazole

0:28:28 Managing acute breakthrough agitation

0:31:10 Novel agents for agitation on the horizon

0:32:27 Collaborating with Centers of Medicare and Medicaid on using antipsychotic agents in long term care facilities

0:35:44 Summary