Asleep vs Awake Deep Brain Stimulation for Parkinson Disease


A study that compared motor and nonmotor outcomes of DBS for Parkinson disease may show promise for patients' quality of life.

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Published in the journal Neurology,1 a study comparing 30 patients with Parkinson disease (PD) that underwent asleep deep brain stimulation (DBS) using intra operative CT image guidance, with 39 patients that had undergone awake DBS for PD.

Asleep DBS improved motor function over 6 months as well as, or better than, awake DBS and was superior when it came to fluency of speech and quality of life. Another potential option for patients with PD.



1. Brodsky MA, Anderson S, Murchison C, et al. Clinical outcomes of asleep vs awake deep brain stimulation for Parkinson disease. Neurology. 2017;89:1944-1950.

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