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Interesting Neuro: Staging Alzheimer & TBI Findings

Our August news includes a potential classification system for Alzheimer disease, new findings in a 3D model of TBI, and migraine treatments.

We present a selection of interesting neurology articles for the month of August in the following slides. See the slide legends for links to the article summaries.

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Interesting Neurology: Staging Alzheimer & TBI Findings. August 2016.

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A/T/N: an Unbiased Descriptive Classification Scheme for Alzheimer Disease Biomarkers. Abstract link. **** Evaluation of Tau Imaging in Staging Alzheimer Disease and Revealing Interactions Between β-Amyloid and Tauopathy. Abstract link.

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A Phase II Study of Fornix Deep Brain Stimulation in Mild Alzheimer’s Disease. Abstract link. ****TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia. Abstract Link.

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Seizures in Dominantly Inherited Alzheimer Disease. Abstract link. **** The Value of 24-Hour Video-EEG in Evaluating Recurrence Risk Following a First Unprovoked Seizure: a Prospective Study. Abstract link.

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Chronic Migraine Headache Prevention with Noninvasive Vagus Nerve Stimulation. Abstract link. ****Cefaly II, a Smaller Migraine Preventing Nerve Stimulator. Abstract link.

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Assessing Response to Interferon-β in a Multicenter Dataset of Patients with MS. Abstract link. ****Reduced Inflammation in Relapsing-Remitting Multiple Sclerosis After Therapy Switch to Rituximab. Abstract link.

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Phos-tag Analysis of Rab10 Phosphorylation by LRRK2: a Powerful Assay for Assessing Kinase Function and Inhibitors. Abstract link. ****Subtypes of Mild Cognitive Impairment in Patients with Parkinson’s Disease: Evidence from the LANDSCAPE Study. Abstract link.

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Global and Regional Effects of Potentially Modifiable Risk Factors Associated with Acute Stroke in 32 Countries (INTERSTROKE): a Case-Control Study. Abstract link. ****Prestroke Vascular Pathology and the Risk of Recurrent Stroke and Poststroke Dementia. Abstract link.

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Strain and Rate-Dependent Neuronal Injury in a 3D in vitro Compression Model of Traumatic Brain Injury. Abstract link.****Head Impact Magnitude in American High School Football. Abstract link.

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Timing of Pharmacologic Venous Thromboembolism Prophylaxis in Severe Traumatic Brain Injury: a Propensity-Matched Cohort Study. Abstract link.****Brain Structure and Function Associated with a History of Sport Concussion: A Multi-Modal Magnetic Resonance Imaging Study. Abstract link.

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Zika and the Risk of Microcephaly. Abstract link. ****Zika Virus Challenges for Neuropsychiatry. Abstract link.

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