Screening for Alzheimer’s Disease: Facilitating an Early Diagnosis for Prompt Intervention
In this episode of MEDcast, expert geriatric psychiatrists explore the urgent need for effective diagnostic methods that can detect Alzheimer’s disease at an early stage. We will discuss blood-based biomarkers and other advancements that can help screen Alzheimer’s disease non-invasively and early in the disease course.
To watch the video series component of this episode, click here.
0:00 Introduction
1:25 An overview of the current standard of care in of Alzheimer’s disease
4:55 Pathophysiology of Alzheimer’s disease
6:58 Aducanumab and lecanemab for Alzheimer’s disease
9:45 Mechanism of action of anti-amyloid agents
11:19 Leaky cell theory in Alzheimer's disease
12:35 Efficacy and safety of aducanumab and lecanemab
13:26 Safety of emerging agents in Alzheimer’s disease
16:37 Practical implementation of lecanemab
19:23 Challenges in CMS coverage for treatments of Alzheimer’s
24:05 Efficacy and safety of Donanemab
25:35 Overcoming clinical inertia around emerging agents in Alzheimer’s disease
29:30 A look into the future of management of Alzheimer’s disease
31:30 Summary
