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Cure Rare Disease Identifies Toxicity Responsible for DMD Gene Therapy Death

Caution is warranted for older patients with Duchenne muscular dystrophy who are receiving gene therapy, according to details of a patient death in a single patient trial.

Read All About It: How On-Demand Therapy Has Changed the PD Landscape

As therapeutic development has advanced in Parkinson disease management, the introduction of on-demand options have extended ON time for patients and altered the paradigm of care.

Challenges and Opportunities Bringing Lecanemab to Neurology Community Clinics 

A group of experts from The Neuron Clinic shared their experience developing a novel inclusive clinical program to treat patients with early Alzheimer disease using lecanemab.

Clinical Considerations for Pharmacologic Approaches to Functional Seizures: Benjamin Tolchin, MD, FAAN

The director of the Center for Clinical Ethics at Yale New Haven Health outlined how the AAN guidelines address the role of pharmacologic therapies in functional seizures, including what evidence exists and when medications should or should not be used. [WATCH TIME: 3 minutes]

Managing Nonmotor Symptoms: Psychosis in Parkinson Disease

Psychosis is estimated to affect more than half of patients with Parkinson disease, and there is a growing need for improved management and therapeutic development.

Dravet Syndrome Awareness Month: Ways to Get Involved

Mary Meskis, executive director of the Dravet Syndrome Foundation, provided a opportunities the organization is offering in honor of Dravet Syndrome Awareness Month.

Doxecitine/Doxribitine Approval Redefines Care in Thymidine Kinase 2 Deficiency: Fabian Somers, PhD

The vice president and Asset Head of Rare and Ultra-Rare Diseases at UCB discussed the landmark FDA approval of doxecitine/doxribitine, the first-ever therapy for thymidine kinase 2 deficiency (TK2d). [WATCH TIME: 3 minutes]

Next Frontier of Research in Multiple Sclerosis Remyelination

The pair of neurologists highlight key advances needed in imaging, trial design, and preclinical modeling to drive remyelination breakthroughs in MS.

Treating Multiple Sclerosis Throughout the Life Cycle of Disease

NeurologyLive® Brain Games: March 20, 2022

Test your neurology knowledge with NeurologyLive®'s weekly quiz series, featuring questions on a variety of clinical and historical neurology topics. This week's topic is optic neuritis and neuromyelitis optica spectrum disorder (NMOSD).

Navigating Treatment Decision-Making in Multiple Sclerosis

In a paradigm with many options, once multiple sclerosis is confirmed as a patient’s diagnosis, physicians are left with 1 question: What do we choose for long-term treatment?

Amplifying Patient Voices Through LGMD Awareness Day: Carol Abraham

The founder of the LGMD Foundation provided context on the significance behind LGMD Awareness Day, an initiative dedicated toward uplifting the limb-girdle muscular dystrophy community. [WATCH TIME: 6 minutes]

The Evolutionary Arch of Stereoelectroencephalography in the United States

SEEG has transformed the surgical investigation of refractory epilepsy, enabling clinicians to map complex seizure networks with precision, leading to more targeted treatment options for patients.

Women's Neurology: Perspectives from the Ann S. Bowers Women's Brain Health Initiative

Nina Miolane, PhD, and Amy Kuceyeski, PhD, the codirectors of the Ann S. Bowers Women's Brain Health Initiative AI Core, provided their commentary on the challenges and progress made in women’s neurology.

Episode 146: Overviewing Donanemab’s New Dosing Regimen: Lowering ARIA Risk in Alzheimer Care

Mind Moments®, a podcast from NeurologyLive®, brings you an exclusive interview with John Sims, MD. [LISTEN TIME: 17 minutes]

Oscillations in Non-REM Sleep Offer New Insight Into Alzheimer Disease Biology: Bryce Mander, PhD

The associate professor of psychiatry and human behavior at UC Irvine explored how analyzing specific sleep oscillations may uncover early neurodegenerative changes and guide future therapeutic targets. [WATCH TIME: 4 minutes]

At the Intersection of Oncology and Neurology: Increasing Recognition of Paraneoplastic Neurologic Syndromes

Since paraneoplastic neurologic syndromes remain underrecognized in oncology, experts recently discussed diagnostic challenges, treatment strategies, and the need for clinical vigilance.

Equity in the Media and Academia

There should be a holistic approach to how the systems in place affect equity: how medicine is practiced and research is conducted, the structure of academic institutions, and how media influence our perceptions of neurologic conditions.

FDA Approves Mirdametinib for NF1-Associated Plexiform Neurofibromas in Adults and Children

The kinase inhibitor was approved for patients with neurofibromatosis type 1 (NF1) who have symptomatic plexiform neurofibromas (PN) not amenable to complete resection.

Discussing the Transition from Pediatric to Adult Epilepsy Care: Josiane Lajoie, MD

The director of pediatric epilepsy at NYU Langone Medical Center shared expert insights on improving transitions from pediatric to adult epilepsy care. [WATCH TIME: 3 minutes]

Overviewing Phase 2 Data of Imlifidase in Guillain-Barré Syndrome: Elisabeth Sonesson, PhD

The vice president and franchise lead of Autoimmune at Hansa Biopharma provided clinical insights on latest phase 2 safety and efficacy data on imlifidase, an IgG-cleaving antibody, in Guillain-Barré syndrome. [WATCH TIME: 3 minutes]

COVID-19’s Effect on the Brain

As many as 1 in 3 infected with COVID-19 have longer-term neurological or mental health symptoms.

Emerging Multiple Sclerosis Treatments

From Standard-of-Care Injectables to Next-Generation S1P Receptor Modulators, Newer Treatments Offer Patients Options

The State of Biomarkers in Multiple Sclerosis

As the field of MS care turns its sights on addressing progressive disease, the need for more biomarkers of disease activity and therapeutic target engagement is perhaps greater than ever.

Patient Evaluation for Excessive Daytime Sleepiness

Excessive daytime sleepiness is a hallmark of a number of sleep disorders, and ensuring the proper diagnosis and management of those presenting with it is crucial to care.