Sleep Medicine

The Psychosocial Impact of COVID-19 in Neurology Departments

September 10, 2020

Leah Croll, MD, a neurology resident on the front lines of the COVID-19 pandemic, shares details from her study on the psychosocial impact on physicians and her first-hand experience.

Lacosamide Meets Primary End Point, Lemborexant Well-Tolerated in Elders, Cala Trio Reduces Hand Tremor

September 05, 2020

Neurology News Network for the week ending September 5, 2020.

Pitolisant Shows No Cardiac Safety Signals in Narcolepsy

September 04, 2020

Despite previous literature documenting cardiovascular disease comorbidity in patients with narcolepsy, pitolisant treatment did not demonstrate any cardiac safety signals.

Longitudinal Sleep Problems in Children Linked With Negative Well-Being

September 02, 2020

The findings support the integration of sleep assessments into routine developmental screenings in school and primary care settings.

Solriamfetol Improves Excessive Daytime Sleepiness and Driving Performance Ability

September 01, 2020

The FDA-approved agent showed significant impact in decreasing standard deviation of lateral position, a measure used to assess driving performance.

Pitolisant Improves Daytime Sleepiness and Cataplexy in Severely Burdened Patients

September 01, 2020

Pooled data from 2 clinical trials of the H3-receptor antagonist/inverse agonist show it improved cataplexy and excessive daytime sleepiness in patients with narcolepsy who were most hampered by symptoms.

Lemborexant Demonstrates Efficacy in Elders

September 01, 2020

Already FDA approved for the treatment of insomnia in adults, lemborexant’s ability to improve sleep outcomes in the elderly was highlighted in a study presented at SLEEP 2020.

Selective Inverse Agonists of the Histamine 3 Receptor as Treatment for Narcolepsy

August 29, 2020

Managing narcolepsy via behavioral strategies to improve excessive daytime sleepiness may be challenging but has shown some added efficacy when combined with pharmacological treatment for EDS.

NeurologyLive Friday 5 - August 28, 2020

August 28, 2020

Take 5 minutes to catch up on NeurologyLive's highlights from the week ending August 28, 2020.

The Importance of Healthy Living in Patients With Narcolepsy

August 28, 2020

Healthy lifestyle choices are an integral part of disease management for patients with narcolepsy who face an increased prevalence of comorbid cardiovascular and metabolic conditions.

Lemborexant Improves Sleep Outcomes Following Placebo Randomization Switch

August 27, 2020

Benefit from lemborexant was evident after 1 month of switching from placebo to the active treatment and was sustained through the entirety of the 12-month trial.