SRK-015 Shows Positive Proof-of-Concept in Spinal Muscular Atrophy
The 12-month results from the phase 2 TOPAZ clinical trial are anticipated by the second quarter of 2021, according to Scholar Rock.
Continuous Early Ocrelizumab Provides Greater Sustained Benefits in Primary Progressive MS
The percent change from baseline was lower in those who initiated ocrelizumab early than those initially on placebo for both T2 lesion volume and T1 hypointense lesion volume.
Raman Malhotra, MD: Increasing the Attention on Insomnia
The associate professor of neurology at Washington University in St. Louis spoke to the need to improve the awareness for insomnia, which remains one of the most common sleep disorders.
Guidelines Released for Alzheimer- and Stroke-Related Care in Down Syndrome
In addition to recommendations for Alzheimer disease screening, the guidelines also covered stroke risk-related assessments which should be conducted for those with Down syndrome.
Genetic Risk for Alzheimer Disease Plays Role in Speech-In-Noise Hearing
The findings suggest that poor speech-in-noise hearing may be an early marker of underlying dementia processes.
This Week on NeurologyLive
Here's what is coming soon to NeurologyLive.
Anup Patel, MD: International LGS Awareness Day
The section chief of pediatric neurology at Nationwide Children’s Hospital provided his thoughts on raising awareness for Lennox-Gastaut syndrome on International LGS Day.
Caring for Patients With Lennox-Gastaut Syndrome During COVID-19
Anup Patel, MD, section chief of pediatric neurology at Nationwide Children’s Hospital, explained how care for patients with Lennox-Gastaut syndrome has changed throughout the pandemic.
Stroke Intervention: A New Application of Interventional Neuroradiology
New training pathways are needed to close the gap between capable-physician supply and the growing demand for thrombectomy.
Diazepam Granted Fast Track, Nerivio Receives FDA Clearance, Zolmitriptan Gets CRL Following NDA Submission
Neurology News Network for the week ending October 31, 2020.
NeurologyLive Friday 5 — October 30, 2020
Take 5 minutes to catch up on NeurologyLive's highlights from the week ending October 30, 2020.
Therapies in Development for Acute Migraine
Ubrogepant: Treatment for Acute Migraine
Rimegepant: Treatment for Acute Migraine
Patient Selection for Acute Migraine Therapy
Acute Migraine Treatment Goals
Treatment Goals for Acute Migraine
Treating Acute Migraine in the Community Setting
Acute Migraine Treatment: What’s Next?
Real-World Experience With Gepants for Acute Migraine
Gepants for Acute Migraine: Patient Management
Gepants for Acute Migraine: Safety & Efficacy Data
Advances in the Treatment of Acute Migraine
Burden of Migraine
Lamotrigine Use During Pregnancy Not Associated With Risk of Autism, ADHD in Children
In the largest study of its kind to date, researchers at Indiana University attempt to elucidate previously inconclusive literature on antiseizure drugs, autism, and ADHD.
Cognitive Function Domains Not Improved With Lowered Systolic Blood Pressure
The researchers concluded that the effect of lowered blood pressure might not be evident in specific domains of cognitive function, but instead distributed across multiple domains.
Jennifer Frontera, MD: Neurologic Implications of COVID-19 Infection
The professor of neurology at the NYU Langone Grossman School of Medicine gave her reaction to the data she and colleagues published on neurologic disorders in patients with COVID-19.
High-Dose Biotin Fails to Improve Disability in Progressive MS
The SPI2 study did not replicate the improvements observed in prior study, instead suggesting that biotin (MD1003; MedDay Pharmaceuticals) is ineffective in patients with progressive MS.
Blarcamesine Safe in Phase 2 Parkinson Disease Dementia Study
The company is planning a pivotal trial of blarcamesine in Parkinson disease dementia after submitting results of the phase 2 study to the FDA for regulatory guidance.
Joe Verghese, MBBS, MS: Characteristics of Motoric Cognitive Risk Syndrome
The director of the Montefiore Einstein Center for the Aging Brain detailed the symptoms of motoric cognitive risk syndrome and how they compare to more typical mild cognitive impairment.