Remote Monitoring Patients Through Smartphone Applications: Michelle Chen, PhD
The neuropsychologist at Rutgers University spoke about the benefits of using smartphone applications to remotely monitor patients based on her most recent published study. [WATCH TIME: 3 minutes]
Management of Alzheimer Disease With Lecanemab
Sharon Cohen, MD, FRCPC, provided an investigator perspective on the use of lecanemab for patients with Alzheimer disease and what the clinician community can take away from the trials.
Uncovering New, Synergistic Ways to Treat Tuberous Sclerosis Complex: Darcy Krueger, MD, PhD
The director of the Tuberous Sclerosis Clinic at Cincinnati Children’s provided insight on whether the timing and combination of certain therapeutics may impact the long-term care for patients with tuberous sclerosis complex. [WATCH TIME: 3 minutes]
Presence of PIRA Following First Demyelinating Event Worsens Long-Term Outcomes in MS
PIRA was associated with, for most patients, a sustained accumulation of disability, which was strongly associated with unfavorable long-term outcomes.
CDC and FDA Announce Stroke Safety Concern Related to Pfizer-BioNTech Bivalent COVID-19 Vaccine
Despite previous data suggesting no link, the CDC and FDA will continue to review all evidence for possible increased risk of ischemic stroke.
Alterations in Gylmphatic Activity Not Significant in Different Narcolepsy Types, Correlated With PSG Parameters
Glymphatic function demonstrated no significant difference in patients with type 1 and type 2 narcolepsy in comparison with healthy controls.
Smartphone Keystrokes Dynamics and Cognitive Function in MS: Michelle Chen, PhD
The neuropsychologist at Rutgers University, in New Brunswick, New Jersey, spoke about her most recent published study on assessing keystrokes on a smartphone in patients with multiple sclerosis. [WATCH TIME: 4 minutes]
Research Identifies Protective Drugs Toward Parkinson Disease, Warranting Future Consideration
Plain sulfonamide diuretics was identified as a drug chemical subgroup potentially inversely associated with Parkinson disease risk, while weaker signals included insulin and ß2-adrenergic agonists.
Navigating Treatment Decisions, Complications for Chronic Migraine: Dolores Santamaria, MD
The director of the Headache Center at Allegheny Health Network discussed whole-body therapeutic approaches to chronic migraine, and the difficulties with finding an effective, long-term strategy. [WATCH TIME: 8 minutes]
This Week on NeurologyLive® — January 16, 2023
Here's some of what is coming soon to NeurologyLive® this week.
High-Dose Ulotaront Reduces REM Sleep Without Atonia in Healthy Individuals
Patients who had higher baseline REM without atonia levels were associated with the largest treatment effects on RSWA with a single 50 mg dose of ulotaront.
Poststroke Epilepsy Management With Antiseizure Medication: Carolina Ferreira Atuesta, MD, MSc
At the 2022 AES Conference, the scientific researcher and clinical manager at the Icahn School of Medicine at Mount Sinai talked on seizure management with medication in poststroke patients. [WATCH TIME: 3 minutes]
NeurologyLive® Brain Games: January 15, 2023
Test your neurology knowledge with NeurologyLive®'s weekly quiz series, featuring questions on a variety of clinical and historical neurology topics. This week's topic is neuromuscular disorders.
Understanding ALZ-801’s Impact on Alzheimer Pathologies, Brain Atrophy
Susan Abushakra, MD, chief medical officer at Alzheon, provided insight on findings from a phase 2 study in which ALZ-801 showed beneficial effects on cognition, Aß 42/40, and brain atrophy.
How Robotics Are Revolutionizing the Future of Neurosurgery: Richard Williamson, MD, FAANS
The neurosurgeon at Allegheny Health Network detailed the potential for robotics in neurosurgery over the coming years, and the vast improvements in comfortability during these procedures. [WATCH TIME: 3 minutes]
24-Hour Levodopa Solution Improves ON Time, Eisai Submits sBLA for Traditional Approval of Lecanemab, Rare Case of Seronegative NMOSD Identified
Neurology News Network for the week ending January 14, 2022. [WATCH TIME: 4 minutes]
Significance of a Potential Traditional Approval of Lecanemab
Sharon Cohen, MD, FRCPC, offered her insight on the significance of the lecanemab approval and what it means for patients with Alzheimer disease.
NeurologyLive® Friday 5 — January 13, 2023
Take 5 minutes to catch up on NeurologyLive®'s highlights from the week ending January 13, 2023.
Systematic Study Identifies Association Between Incident Parkinson Disease and Antiepileptic Drug Use
Not previously explored, new findings showed links between antiseizure drug prescriptions and incident PD, with trends towards increased risk in those with greater number of prescription issues and multiple AEDs.
Improving Awareness of Cognitive Decline and Building on Lecanemab’s Success: Sharon Cohen, MD, FRCPC
The behavioral neurologist and medical director of the Toronto Memory Program provided perspective on the steps the general public can take toward reducing the risk of Alzheimer disease and initiating treatment early when needed. [WATCH TIME: 4 minutes]
Episode 80: Advancing Treatment for Rare Neuromuscular Disorders
Mind Moments®, a podcast from NeurologyLive®, brings you an exclusive interview with Sarah Boyce. [LISTEN TIME: 21 minutes]
Neurelis Files IND for Potentially First Therapy to Treat Cerebral Cavernous Malformations
In preclinical animal models, NRL-1049 showed an ability to decrease ROCK-2 activation, a pathway that is hyperactivated in patients with cerebral cavernous malformations.
Rarity of Seizures During REM Sleep: Milena Pavlova, MD
The associate professor at Harvard Medical School and neurologist at the Brigham and Women's Hospital shared the current research on rapid eye movement in sleep and seizures. [WATCH TIME: 3 minutes]
Supportive Self-Management Program Shows No Efficacy in Improving QOL for Chronic Migraine
The trial found no evidence of any clinically relevant benefit from the CHESS intervention across multiple outcomes at multiple time points, nor in any sensitivity or subgroup analyses.
Functionality of Robotic Exoscope to Improve Neurosurgery: Richard Williamson, MD, FAANS
The neurosurgeon at Allegheny Health Network provided background on a new, state-of-the-art tool designed to ultimately improve neurosurgical procedures. [WATCH TIME: 3 minutes]
FDA Accepts sBLA for Revance’s Cervical Dystonia Treatment DaxibotulinumtoxinA
DaxibotulinumtoxinA, the first and only peptide formulated neuromodulator, has been shown to be safe and well tolerated in doses of 125 and 250 units, with clinically meaningful effect observed by both patients and clinicians.
Clinical Outlook on ND0612 in Parkinson’s Disease
Ryan Case, PhD, head of clinical medical affairs at NeuroDerm, spoke about the main findings from the phase 3 BouNDless trial of ND0612 for Parkinson disease.
Worse Clinical Outcomes, Higher Mortality Rates, and Shorter Lifespans in Epilepsy and Dementia: Ifrah Zawar, MD
The assistant professor of neurology at the University of Virginia spoke at the 2022 AES Conference about clinical outcomes of patients with dementia who experience seizures. [WATCH TIME: 5 minutes]
Understanding the Widespread Impacts of The Ohio State University Wexner Medical Center’s Teleneurology Program
The virtual care program built by The Ohio State University Wexner Medical Center allows for expanded access to patient care in rural areas, improved decision-making, and hands-on experience for young neurologists.
Poststroke Epilepsy and Cerebrovascular Disease: Carolina Ferreira Atuesta, MD, MSc
The scientific researcher and clinical manager at the Icahn School of Medicine at Mount Sinai, spoke about a talk given at the 2022 AES conference on seizures after ischemic. [WATCH TIME: 5 minutes]
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