Recognizing Health Disparities in Infantile Spasms at Local and National Levels: Kerri Neville, MD
The pediatric neurologist and epileptologist at the University of Michigan's Mott Children's Hospital spoke at the 2022 AES conference about disparities that currently exist in epilepsy care. [WATCH TIME: 4 minutes]
Linking the Latest Research to Clinical Care in MS: Robert Bermel, MD
The director of the Mellen Center for MS at Cleveland Clinic offered an overview of the State of the Science Summit that was held on November 10, 2022, featuring a panel of expert clinicians. [WATCH TIME: 4 minutes]
Improving Biomarker Selection and Treating the Underlying Pathology of Dementia With Lewy Bodies
James Galvin, MD, MPH, director of the Comprehensive Center for Brain Health at the University of Miami Miller School of Medicine, provided insight on the unmet needs for dementia with Lewy bodies, and whether success in Alzheimer disease can help.
Patient-Reported Outcomes Improved Through Earlier Initiation of MS Treatment
Using a cohort of more than 2500 patients with MS on disease-modifying therapies, treatment initiation within the first 2 years of disease onset was more beneficial on patient-reported outcomes than 2-4 years postonset.
Understanding Irsenontrine’s Role Among Neurodegenerative Disorders: Michael Irizarry, MD, PhD
The senior VP of clinical research at Eisai discussed findings from a phase 2 study assessing irsenontrine in patients with dementia with Lewy bodies and Parkinson disease dementia. [WATCH TIME: 4 minutes]
This Week on NeurologyLive® — December 19, 2022
Here's some of what is coming soon to NeurologyLive® this week.
Institutional Perspectives in Neurology, Chaired by Robert Bermel, MD
Chaired by Robert Bermel, MD, of Cleveland Clinic, the presentations also feature Jeffrey Cohen, MD; Amy Kunchock, MBBS, MMed; and Brandon Moss, MD. [WATCH TIME: 1 hour, 30 minutes]
Sudden Unexpected Death in Epilepsy Linked With Sleep: Sanjeev Kothare, MD
The division director of pediatric neurology, and director of the pediatric sleep program at Cohen, Children's Medical Center, Northwell Health, spoke about sudden unexpected death in epilepsy and sleep at the 2022 AES Conference. [WATCH TIME: 3 minutes]
NeurologyLive® Brain Games: December 18, 2022
Test your neurology knowledge with NeurologyLive®'s weekly quiz series, featuring questions on a variety of clinical and historical neurology topics. This week's topic is multiple sclerosis.
Short Sleep Duration, Poor Sleep Quality Both Associated With Weight Regain in Obese Individuals
Short objective sleep duration was associated with weight regain and attenuated improvements in body composition one year after weight loss, independent of intervention allocation, age, and sex.
Themes From Exercise Trials in Multiple Sclerosis Improves Quality of Future Research
A recent review from the National MS Society revealed eight themes based on previous clinical trials focused on exercise and physical activity in MS.
Genetic Links to PML Identified, MARINA Trial Findings Announced, Educational Videos Improve CPAP Adherence
Neurology News Network for the week ending December 17, 2022. [WATCH TIME: 4 minutes]
NeurologyLive® Friday 5 — December 16, 2022
Take 5 minutes to catch up on NeurologyLive®'s highlights from the week ending December 16, 2022.
COVID-19 and the Brain: Understanding the Neurological Effects of the Virus as the Pandemic Evolves
Almost 3 years since the beginning of the pandemic, continuous research efforts have begun to paint a better picture of the impact the virus has on the brain and the central nervous system.
The Relationship Between Sleep Disorders, Pediatric Epilepsy, and AntiSeizure Medications: Sanjeev Kothare, MD
The division director of pediatric neurology, and director of the pediatric sleep program at Cohen Children's Medical Center of Northwell Health, spoke about the association between sleep disorders and pediatric epilepsy at the 2022 AES annual meeting. [WATCH TIME: 3 minutes]
Managing Chronic Migraine Through Treatment and Lifestyle Decisions: Dolores Santamaria, MD
The director of the Headache Center at Allegheny Health Network provided perspective on whether focusing in on medications or lifestyle choices has better impacts on improving chronic migraine. [WATCH TIME: 4 minutes]
Episode 79: A New Monoclonal for Alzheimer Disease
Mind Moments®, a podcast from NeurologyLive®, brings you an exclusive interview with Marwan Sabbagh, MD, FAAN. [LISTEN TIME: 21 minutes]
Exposure to Low Concentration Carbon Dioxide Before Bedtime Improves Sleep Time
Findings from a recent randomized study demonstrated effective sleep maintenance of insomnia, as shown by increased sleep time and reduced awakenings, with low concentration of carbon dixoide.
First-Ever Genetic Links Found in Progressive Multifocal Leukoencephalopathy
In the largest collected of PML DNA samples, the study identified 4 immune-linked, high effect size, rare variants for use in an iatrogenic PML risk genetic test.
Increased Risk of Insomnia in Transgender Youths With Mental Health Disorders: Ronald Gavidia, MD, MS
The clinical assistant professor in the division of Sleep Medicine, Department of Neurology, University of Michigan spoke about the associations of mental health with insomnia in transgender youth. [WATCH TIME: 5 minutes]
Myotonic Dystrophy Agent AOC 1001 Demonstrates Successful Targeted Delivery of RNA
AOC 1001, an agent consisting of a proprietary monoclonal antibody that binds to the transferrin receptor 1, was safe, tolerable, and showed significant reductions in DMPK, a disease-related mRNA.
High Risk of Sleep Disorder Burden in Transgender Youth: Ronald Gavidia, MD, MS
The clinical assistant professor in the division of Sleep Medicine, Department of Neurology, University of Michigan, spoke about sleep disorders associated with transgender youths. [WATCH TIME: 4 minutes]
Educational Videos Improve CPAP Adherence in Obstructive Sleep Apnea
Although the effects of the educational intervention weren’t seen at 3 months, investigators noticed significant differences relative to standard of care at 12 months.
Phenotypes of Chronic Insomnia in Early Childhood Proposed to Improve Identification
A recent review suggests that children might be affected by specific types of insomnia and that their treatment should be more suitable to their classified insomnia phenotype.
NeuroVoices: Susan Abushakra, MD, on the Potential Role of ALZ-801 Within the Alzheimer Treatment Landscape
The chief medical officer of Alzheon detailed the efficacy, safety, and potential of ALZ-801, an investigational anti-amyloid therapy being assessed in high-risk individuals with early Alzheimer disease.
BrainStorm Submits Type A Meeting Request Regarding NurOwn ALS Treatment
In a phase 3 trial, NurOwn failed to meet its primary end point of change on ALSFRS-R; however, the therapy showed significant benefits in those with less severe forms of ALS.
Sunobinop Demonstrates Positive Findings in Reducing Wake Time After Falling Asleep
A recent phase 2 study showed a significant decline in wakefulness after sleep onset across both doses of sunobinop for individuals with insomnia recovery from alcohol use disorder.
The Effect of Aging in Multiple Sclerosis and the Model of Care: Ruth Ann Marrie, MD, PhD, FRCPC
The professor of medicine at the University of Manitoba discussed the need to change how multiple sclerosis is characterized, and how aging contributes to increased disease progression. [WATCH TIME: 4 minutes]
Hydromethylthionine Mesylate’s Place as a Potential Tau Aggregator of Alzheimer Disease
Bjoern Schelter, MD, Data Analytics and Biostatistics lead at TauRx, provided background on the efficacy, safety, and role of HMTM as a treatment for cognition in pre-Alzheimer disease stages like mild cognitive impairment.
FDA Action Update, November 2022: Application Acceptances and a Refusal to File
Catch up on any of the neurology news headlines you may have missed over the course of the last month, compiled all into one place by the NeurologyLive® team.
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